Clinical Physiology of Circulation

ISSN 1814-6910 (Print)
ISSN 2410-9134 (Online)

 

Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery


Issue's catalogue ➤ КФК. 2021; 18 (1): 1-92 ➤ Головная боль и сердечно-сосудистые заболевания

Headache and cardiovascular diseases

Authors: Emets E.V.1,2, 2, Shumilina M.V. 2

Company:
1 Institute of Training of Highly Qualified Personnel and Professional Education of the Bakoulev National Medical Research Center for Cardiovascular Surgery, Moscow, 121552, Russian Federation
2 Voronezh Regional Clinical Hospital No. 1, Voronezh, 394066, Russian Federation

E-mail: Сведения доступны для зарегистрированных пользователей.

DOI: https://doi.org/10.24022/1814-6910-2021-18-1-16-23

UDC: 616.857+616.1

Link: Clinical Physiology of Blood Circulaiton. 2021; 1 (18): 16-23

Quote as: Emets E.V., Shumilina M.V. Headache and cardiovascular diseases. Clinical Physiology of Circulation. 2021; 18 (1): 16–23 (in Russ.). DOI: 10.24022/1814-6910-2021-18-1-16-23

Keywords:  migraine heart cephalgia cardiovascular diseases

Received / Accepted:  13.11.2020 / 27.11.2020

Full text:  

Abstract

Headaches (especially migraines with aura) are consistently associated with an increased risk of heart disease. The exact pathophysiological mechanisms of associations of headache with cardiovascular pathology remain unclear, and the literature data are often contradictory. However, migraines with aura are associated with blood clotting factors and systemic vascular endothelial dysfunction, which can increase the risk of arterial thrombosis and myocardial infarction. Individuals with migraines (especially those with aura) also have an increased risk of comorbidities and complications (such as arterial dissection) that may contribute to or cause myocardial infarction. In addition, changes in the cardiovascular system and the ischemic threshold of the heart muscle in people suffering from migraines with aura may also increase the risk of myocardial infarction, especially in conditions of vascular stress (for example, arterial embolism).

References

  1. Vos Th., Flaxman A.D., Naghavi M., Lozano R., Michaud C., Ezzati M. et al. Years lived with disability Обзоры 21 Клиническая физиология кровообращения. 2021; 18 (1). DOI: 10.24022/1814-6910-2021-18-1-16-23(YLD) for 1160 squealed of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012; 380 (9859): 2163–96. DOI: 10.1016/S0140-6736(12)61729-2
  2. GBD 2015 Neurological Disorders Collaborator Group Global, regional, and national burden of neurological disorders during 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet Neurol. 2017; 16 (11): 877–89.
  3. The International Classification of Headache Disorders, 3rd edition (ICHD-3). Cephalalgia. 2018; 38 (1): 1–211. DOI: 10.1177/0333102417738202
  4. Sacco S., Ornello R., Ripa P., Tiseo C., Degan D., Pistoia F. et al. Migraine and risk of ischaemic heart disease: a systematic review and meta-analysis of observational studies. Eur. J. Neurol. 2015; 22: 1001–11. DOI: 10.1111/ene.12701
  5. Kurth T., Winter A.C., Eliassen A.H., Dushkes R., Mukamal K.J., Rimm E.B. et al. Migraine and risk of cardiovascular disease in women: prospective cohort study. BMJ. 2016; 353: i2610. DOI: 10.1136/bmj.i2610 6. Linstra K.M., Ibrahimi K., Terwindt G.M., Wermer M.J.H., MaassenVanDenBrink A. Migraine and cardiovascular disease in women. Maturitas. 2017; 97: 28–31. DOI: 10.1016/j.maturitas.2016.12.008
  6. Mahmoud A.N., Mentias A., Elgendy A.Y., Qazi A., Barakat A.F., Saad M. et al. Migraine and the risk of cardiovascular and cerebrovascular events: a metaanalysis of 16 cohort studies including 1 152 407 subjects. BMJ. 2018; 8: e020498. DOI: 10.1136/bmjopen2017-020498
  7. Adelborg K., Szépligeti S.K., Holland-Bill L., Ehrenstein V., Horváth-Puhó E., Henderson V.W. et al. Migraine and risk of cardiovascular diseases: Danish population based matched cohort study. BMJ. 2018; 360: k96. DOI: 10.1136/bmj.k96 9. Sen S., Androulakis X.M., Duda V., Alonso A., Chen L.Y., Soliman E.Z. et al. Migraine with visual aura is a risk factor for incident atrial fibrillation: a cohort study. Neurology. 2018; 91: e2202–10. DOI: 10.1212/WNL.0000000000006650
  8. Elgendy I.Y., Nadeau S.E., Merz C.N., Pepine C.J. Migraine headache: an under-appreciated risk factor for cardiovascular disease in women. J. Am. Heart Ass. 2019; 8: e014546. DOI: 10.1161/JAHA.119.014546
  9. Saeed A., Rana K.F., Warriach Z.I., Tariq M.A. Association of migraine and ischemic heart disease: a review. Cureus. 2019; 11 (9): e5719. DOI: 10.7759/cureus.5719
  10. Kurth T., Rohmann J.L., Shapiro R.E. Migraine and risk of cardiovascular disease. BMJ. 2018; 360: k275. DOI: 10.1136/bmj.k275
  11. Hippisley-Cox J., Coupland C., Brindle P. Development and validation of QRISK3 risk prediction algorithms to estimate future risk of cardiovascular disease: prospective cohort study. BMJ. 2017; 357: j2099. DOI: 10.1136/bmj.j2099
  12. O/ie L.R., Kurth T., Gulati S., Dodick D.W. Migraine and risk of stroke. J. Neurol. Neurosurg. Psych. 2020; 91: 593–604. DOI: 10.1136/jnnp-2018-318254
  13. Elseweidy M.M. The cause of the morning headache is a violation of the venous outflow from the head due to the oncoming flow therapeutic potential of 10-DHGD and/or Pentoxifyllin against aorta calcification in high dietary cholesterol-fed rabbits. Abstract. In: Second International Conference on Dental and Oral Health. 2018, November 26–27; Madrid, Spain.
  14. Ermoshkin V.I. The cause of the morning headache is a violation of the venous outflow from the head due to the oncoming flow. J. Biomed. Pharm. Sci. 2018; 1 (2): 113–5. 17. Ermoshkin V.I. The new theory of heart failure. London; 2017: 15–7. http://heartcongress.conference series.com/europe/abstract/2017/the-new-theoryofheart-failure (дата обращения 17.03.2017)
  15. Folsom A.R., Lutsey P.L., Misialek J.R., Cushman M. A prospective study of migraine history and venous thromboembolism in older adults. Res. Pract. Thromb. Haemost. 2019; 3 (3): 357–63. DOI: 10.1002/rth2.12200
  16. Siegerink B., Rohmann J.L. Impact of your results: beyond the relative risk. Res. Pract. Thromb. Haemost. 2018; 2: 653–57. DOI: 10.1002/rth2.12148 20. Siegerink B., Adelborg K. Migraine and venous thrombosis: another important piece of the puzzle. Res. Pract. Thromb. Haemost. 2019; 3 (3): 309–11. DOI: 10.1002/rth2.12209
  17. Peng K.P., Chen Y.T., Fuh J.L., Tang C.H., Wang S.J. Association between migraine and risk of venous thromboembolism: a nationwide cohort study. Headache. 2016; 56: 1290–9. DOI: 10.1111/head.12885
  18. Asvestas D., Vlachos K., Salachas A., Letsas K.P., Sideris A. Headache: an unusual presentation of acute myocardial infraction. World J. Cardiol. 2014; 6: 514–6. DOI: 10.4330/wjc.v6.i6.514
  19. Wassef N., Ali A.T., Katsanevaki A.Z., Nishtar S. Cardiac cephalgia. Cardiol. Res. 2014; 5: 195–7. DOI: 10.14740/cr361w
  20. Chowdhury A.W., Saleh M.A.D., Hasan P., Amin M.G., Khan T.A., Sabah K.M.N., Kabir S.R. Cardiac cephalgia: a headache of the heart. J. Cardiol. Cases. 2015; 11: 139–41. DOI: 10.1016/j.jccase.2015.02.002
  21. Huang C.C., Liao P.C. Heart attack causes headache – cardiac cephalalgia. Acta Cardiol. Sin. 2016; 32: 239–42. DOI: 10.6515/acs20150628a
  22. MacIsaac R., Jarvis S., Busche K. A case of a cardiac cephalgia. Can. J. Neurol. Sci. 2019; 46: 124–6. DOI: 10.1017/cjn.2018.377
  23. Dell’Aquila A., Sciatti E., Vizzardi E., Metra M. The brain-heart connection: a multiple sclerosis relapse presenting as Takotsubo Syndrome. A case report and literature review. Monaldi Arch. Chest. Dis. 2020; 90 (1): 143–7. DOI: 10.4081/monaldi.2020.1153
  24. Bi Y.C., Gong L. Headache and sick sinus syndrome: a case report. World J. Clin. Cases. 2020; 8 (12): 2629–33. DOI: 10.12998/wjcc.v8.i12.2629
  25. Takagi H., Umemoto T. A meta-analysis of case-control studies of the association of migraine and patent foramen ovale. J. Cardiol. 2016; 67: 493–503. DOI: 10.1016/j.jjcc.2015.09.016
  26. West B.H., Noureddin N., Mamzhi Y., Low C.G., Coluzzi A.C., Shih E.J. et al. Frequency of patent foramen ovale and migraine in patients with cryptogenic stroke. Stroke. 2018; 49: 1123–8. DOI: 10.1161/strokeaha.117.020160 31. Biasco L., Infantino V., Orzan F., Vicentini S., Rovera Ch., Longo G. et al. Impact of transcatheter closure of patent foramen ovale in the evolution of migraine and role of residual shunt. Am. J. Cardiol. 2014; 64: 390–4. DOI: 10.1016/j.jjcc.2014.02.023
  27. Mattle H.P., Evers S., Hildick-Smith D., Becker W.J., Baumgartner H., Chataway J. et al. Percutaneous closure of patent foramen ovale in migraine with aura, a randomized controlled trial. Eur. Heart J. 2016; 37: 2029–36. DOI: 10.1093/eurheartj/ehw027
  28. Tobis J.M., Charles A., Silberstein S.D., Sorensen S., Maini B., Horwitz Ph.A. et al. Percutaneous closure of patent foramen ovale in patients with migraine: the premium trial. J. Am. Coll. Cardiol. 2017; 70: 2766–74. DOI: 10.1016/j.jacc.2017.09.1105
  29. Sommer R.J., Nazif T., Privitera L., Robbins B.T. Retrospective review of thienopyridine therapy in migraineurs with patent foramen ovale. Neurology. 2018; 91: 1002–09. DOI: 10.1212/WNL.0000000000006572
  30. Androulakis X.M., Kodumuri N., Giamberardino L.D., Rosamond W.D., Gottesman R.F., Yim E. et al. Ischemic stroke subtypes and migraine with visual aura in the ARIC study. Neurology. 2016; 87: 2527–32. DOI: 10.1212/WNL.0000000000003428
  31. Табеева Г.Р. Головная боль: Руководство для врачей. 2-е изд., перераб. и доп. М.: ГЭОТАР-Медиа; 2018. [Tabeeva G.R. Headache: Guide for doctors. 2nd ed., reprint. and add. Moscow: GEOTAR-Media; 2018 (in Russ.).
  32. Табеева Г.Р. Головная боль. М.: ГЭОТАР-Медиа; 2020. https://www.rosmedlib.ru/book/ISBN 9785970458648.html (дата обращения 10.11.2020) [Tabeeva G.R. Headache. Moscow: GEOTAR-Media; 2020 (in Russ.). https://www.rosmedlib.ru/book/ISBN9785970458648.html (accessed 10.11.2020)
  33. Ramadan N.M. Headache caused by raised intracranial pressure and intracranial hypotension. Curr. Opin. Neurol. 1996; 9: 214–8. DOI: 10.1097/00019052- 199606000-00011 39. Lipton R.B., Lowenkopf T., Bajwa Z.H., Leckie R.S., Ribeiro S., Newman L.C., Greenberg M.A. Cardiac cephalgia: a treatable form of exertional headache. Neurology. 1997; 49: 813–6. DOI: 10.1212/wnl.49.3.813
  34. Bini A., Evangelista A., Castellini P., Lambru G., Ferrante T., Manzoni G.C., Torelli P. Cardiac cephalgia. J. Headache Pain. 2009; 10: 3–9. DOI: 10.1007/s10194-008-0087-x
  35. Sacco S., Ripa P., Grassi D., Pistoia F., Ornello R., Carolei A. et al. Peripheral vascular dysfunction in migraine: a review. J. Head. Pain. 2013; 14: 80. DOI: 10.1186/1129-2377-14-80
  36. Butt J.H., Franzmann U., Kruuse C. Endothelial function in migraine with aura – a systematic review. Headache. 2015; 55: 35–54. DOI: 10.1111/head.12494
  37. Rambarat C., Elgendy I., Johnson B., Reis S.E., Thompson D.V., Sharaf B.L. et al. Migraine headache and long-term cardiovascular outcomes: an extended follow-up of the women’s ischemia syndrome evaluation. Am. J. Med. 2017; 130: 738–43. DOI: 10.1016/j.amjmed.2016.12.028
  38. Tietjen G.E., Khubchandani J. Vascular biomarkers in migraine. Cephalalgia. 2015; 35: 95–117. DOI: 10.1177/0333102414544976 45. Tietjen G.E., Collins S.A. Hypercoagulability and migraine. Headache. 2018; 58: 173–83. DOI: 10.1111/head.13044
  39. Iljazi A., Ayata C., Ashina M., Hougaard A. The role of endothelin in the pathophysiology of migraine – a systematic review. Curr. Pain Head. Rep. 2018; 22: 27. DOI: 10.1007/s11916-018-0682-8
  40. Kurth T. Migraine a marker of vascular health? Cephalalgia. 2013; 33: 226–7. DOI: 10.1177/0333102412472074
  41. Winsvold B.S., Bettella F., Witoelar A., Anttila V., Gormley P., Kurth T. et al. Shared genetic risk between migraine and coronary artery disease: a genome-wide analysis of common variants. PLoS One. 2017; 12: e0185663. DOI: 10.1371/journal.pone.0185663
  42. Winsvold B.S., Nelson C.P., Malik R., Gormley P., Anttila V., Vander Heiden J. et al. Genetic analysis for a shared biological basis between migraine and coronary artery disease. Neurol. Gen. 2015; 1: e10. DOI: 10.1212/nxg.0000000000000010
  43. Malik R., Freilinger T., Winsvold B.S., Anttila V., Vander Heiden J., Traylor M. et al. Shared genetic basis for migraine and ischemic stroke: a genome-wide analysis of common variants. Neurology. 2015; 84: 2132–45. DOI: 10.1212/wnl.0000000000001606
  44. Pickrell J.K., Berisa T., Liu J.Z., Segurel L., Tung J.Y., Hinds D.A. Detection and interpretation of shared genetic influences on 42 human traits. Nat. Gen. 2016; 48: 709–17. DOI: 10.1038/ng.3570
  45. Азимова Ю.Э., Климов Е.А., Скоробогатых К.В., Сергеев А.В., Кокаева З.Г., Табеева Г.Р. Генетические основы гемиплегической мигрени. Медицинская генетика. 2013; 12 (4): 3–7.
  46. Ruff R.L., Ruff S.S., Wang X.-F. Headaches among operation iraqi freedom/operation enduring freedom veterans with mild traumatic brain injury associated with exposures to explosions. J. Rehabil. Res. Dev. 2008; 45 (7): 941–52. DOI: 10.1682/JRRD.2008.02.0028
  47. Филатова Е.Г., Осипова В.В., Табеева Г.Р., Парфенов В.А., Екушева Е.В., Азимова Ю.Э. и др. Диагностика и лечение мигрени: рекомендации российских экспертов. Неврология, нейропсихиатрия, психосоматика. 2020; 12 (4): 4–14. DOI: 10.14412/2074-2711-2020-4-4-14
  48. Шумилина М.В., Бузиашвили Ю.И. Нарушения венозного церебрального кровообращения у больных с сердечно-сосудистыми заболеваниями. Клиническая физиология кровообращения. 2004; 2: 44–53.
  49. Бокерия Л.А., Бузиашвили Ю.И., Шумилина М.В. Нарушения венозного церебрального кровообращения у больных с сердечно-сосудистой патологией (головная боль, ишемия, артериосклероз). М: Изд-во НЦССХ им. А.Н. Бакулева РАМН; 2003.
  50. Горбунова Е.В., Шумилина М.В. Дефект межпредсердной перегородки и цефалгический синдром. Клиническая физиология кровообращения. 2009; 2: 24–30.
****
  1. Vos Th., Flaxman A.D., Naghavi M., Lozano R., Michaud C., Ezzati M. et al. Years lived with disability squealed of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012; 380 (9859): 2163–96. DOI: 10.1016/S0140-6736(12)61729-2
  2. GBD 2015 Neurological Disorders Collaborator Group Global, regional, and national burden of neurological disorders during 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet Neurol. 2017; 16 (11): 877–89.
  3. The International Classification of Headache Disorders, 3rd edition (ICHD-3). Cephalalgia. 2018; 38 (1): 1–211. DOI: 10.1177/0333102417738202
  4. Sacco S., Ornello R., Ripa P., Tiseo C., Degan D., Pistoia F. et al. Migraine and risk of ischaemic heart disease: a systematic review and meta-analysis of observational studies. Eur. J. Neurol. 2015; 22: 1001–11. DOI: 10.1111/ene.12701
  5. Kurth T., Winter A.C., Eliassen A.H., Dushkes R., Mukamal K.J., Rimm E.B. et al. Migraine and risk of cardiovascular disease in women: prospective cohort study. BMJ. 2016; 353: i2610. DOI: 10.1136/bmj.i2610 6. Linstra K.M., Ibrahimi K., Terwindt G.M., Wermer M.J.H., MaassenVanDenBrink A. Migraine and cardiovascular disease in women. Maturitas. 2017; 97: 28–31. DOI: 10.1016/j.maturitas.2016.12.008
  6. Mahmoud A.N., Mentias A., Elgendy A.Y., Qazi A., Barakat A.F., Saad M. et al. Migraine and the risk of cardiovascular and cerebrovascular events: a metaanalysis of 16 cohort studies including 1 152 407 subjects. BMJ. 2018; 8: e020498. DOI: 10.1136/bmjopen2017-020498
  7. Adelborg K., Szépligeti S.K., Holland-Bill L., Ehrenstein V., Horváth-Puhó E., Henderson V.W. et al. Migraine and risk of cardiovascular diseases: Danish population based matched cohort study. BMJ. 2018; 360: k96. DOI: 10.1136/bmj.k96 9. Sen S., Androulakis X.M., Duda V., Alonso A., Chen L.Y., Soliman E.Z. et al. Migraine with visual aura is a risk factor for incident atrial fibrillation: a cohort study. Neurology. 2018; 91: e2202–10. DOI: 10.1212/WNL.0000000000006650
  8. Elgendy I.Y., Nadeau S.E., Merz C.N., Pepine C.J. Migraine headache: an under-appreciated risk factor for cardiovascular disease in women. J. Am. Heart Ass. 2019; 8: e014546. DOI: 10.1161/JAHA.119.014546
  9. Saeed A., Rana K.F., Warriach Z.I., Tariq M.A. Association of migraine and ischemic heart disease: a review. Cureus. 2019; 11 (9): e5719. DOI: 10.7759/cureus.5719
  10. Kurth T., Rohmann J.L., Shapiro R.E. Migraine and risk of cardiovascular disease. BMJ. 2018; 360: k275. DOI: 10.1136/bmj.k275
  11. Hippisley-Cox J., Coupland C., Brindle P. Development and validation of QRISK3 risk prediction algorithms to estimate future risk of cardiovascular disease: prospective cohort study. BMJ. 2017; 357: j2099. DOI: 10.1136/bmj.j2099
  12. O/ie L.R., Kurth T., Gulati S., Dodick D.W. Migraine and risk of stroke. J. Neurol. Neurosurg. Psych. 2020; 91: 593–604. DOI: 10.1136/jnnp-2018-318254
  13. Elseweidy M.M. The cause of the morning headache is a violation of the venous outflow from the head due to the oncoming flow therapeutic potential of 10-DHGD and/or Pentoxifyllin against aorta calcification in high dietary cholesterol-fed rabbits. Abstract. In: Second International Conference on Dental and Oral Health. 2018, November 26–27; Madrid, Spain.
  14. Ermoshkin V.I. The cause of the morning headache is a violation of the venous outflow from the head due to the oncoming flow. J. Biomed. Pharm. Sci. 2018; 1 (2): 113–5. 17. Ermoshkin V.I. The new theory of heart failure. London; 2017: 15–7. http://heartcongress.conference series.com/europe/abstract/2017/the-new-theoryofheart-failure (дата обращения 17.03.2017)
  15. Folsom A.R., Lutsey P.L., Misialek J.R., Cushman M. A prospective study of migraine history and venous thromboembolism in older adults. Res. Pract. Thromb. Haemost. 2019; 3 (3): 357–63. DOI: 10.1002/rth2.12200
  16. Siegerink B., Rohmann J.L. Impact of your results: beyond the relative risk. Res. Pract. Thromb. Haemost. 2018; 2: 653–57. DOI: 10.1002/rth2.12148 20. Siegerink B., Adelborg K. Migraine and venous thrombosis: another important piece of the puzzle. Res. Pract. Thromb. Haemost. 2019; 3 (3): 309–11. DOI: 10.1002/rth2.12209
  17. Peng K.P., Chen Y.T., Fuh J.L., Tang C.H., Wang S.J. Association between migraine and risk of venous thromboembolism: a nationwide cohort study. Headache. 2016; 56: 1290–9. DOI: 10.1111/head.12885
  18. Asvestas D., Vlachos K., Salachas A., Letsas K.P., Sideris A. Headache: an unusual presentation of acute myocardial infraction. World J. Cardiol. 2014; 6: 514–6. DOI: 10.4330/wjc.v6.i6.514
  19. Wassef N., Ali A.T., Katsanevaki A.Z., Nishtar S. Cardiac cephalgia. Cardiol. Res. 2014; 5: 195–7. DOI: 10.14740/cr361w
  20. Chowdhury A.W., Saleh M.A.D., Hasan P., Amin M.G., Khan T.A., Sabah K.M.N., Kabir S.R. Cardiac cephalgia: a headache of the heart. J. Cardiol. Cases. 2015; 11: 139–41. DOI: 10.1016/j.jccase.2015.02.002
  21. Huang C.C., Liao P.C. Heart attack causes headache – cardiac cephalalgia. Acta Cardiol. Sin. 2016; 32: 239–42. DOI: 10.6515/acs20150628a
  22. MacIsaac R., Jarvis S., Busche K. A case of a cardiac cephalgia. Can. J. Neurol. Sci. 2019; 46: 124–6. DOI: 10.1017/cjn.2018.377
  23. Dell’Aquila A., Sciatti E., Vizzardi E., Metra M. The brain-heart connection: a multiple sclerosis relapse presenting as Takotsubo Syndrome. A case report and literature review. Monaldi Arch. Chest. Dis. 2020; 90 (1): 143–7. DOI: 10.4081/monaldi.2020.1153
  24. Bi Y.C., Gong L. Headache and sick sinus syndrome: a case report. World J. Clin. Cases. 2020; 8 (12): 2629–33. DOI: 10.12998/wjcc.v8.i12.2629
  25. Takagi H., Umemoto T. A meta-analysis of case-control studies of the association of migraine and patent foramen ovale. J. Cardiol. 2016; 67: 493–503. DOI: 10.1016/j.jjcc.2015.09.016
  26. West B.H., Noureddin N., Mamzhi Y., Low C.G., Coluzzi A.C., Shih E.J. et al. Frequency of patent foramen ovale and migraine in patients with cryptogenic stroke. Stroke. 2018; 49: 1123–8. DOI: 10.1161/strokeaha.117.020160 31. Biasco L., Infantino V., Orzan F., Vicentini S., Rovera Ch., Longo G. et al. Impact of transcatheter closure of patent foramen ovale in the evolution of migraine and role of residual shunt. Am. J. Cardiol. 2014; 64: 390–4. DOI: 10.1016/j.jjcc.2014.02.023
  27. Mattle H.P., Evers S., Hildick-Smith D., Becker W.J., Baumgartner H., Chataway J. et al. Percutaneous closure of patent foramen ovale in migraine with aura, a randomized controlled trial. Eur. Heart J. 2016; 37: 2029–36. DOI: 10.1093/eurheartj/ehw027
  28. Tobis J.M., Charles A., Silberstein S.D., Sorensen S., Maini B., Horwitz Ph.A. et al. Percutaneous closure of patent foramen ovale in patients with migraine: the premium trial. J. Am. Coll. Cardiol. 2017; 70: 2766–74. DOI: 10.1016/j.jacc.2017.09.1105
  29. Sommer R.J., Nazif T., Privitera L., Robbins B.T. Retrospective review of thienopyridine therapy in migraineurs with patent foramen ovale. Neurology. 2018; 91: 1002–09. DOI: 10.1212/WNL.0000000000006572
  30. Androulakis X.M., Kodumuri N., Giamberardino L.D., Rosamond W.D., Gottesman R.F., Yim E. et al. Ischemic stroke subtypes and migraine with visual aura in the ARIC study. Neurology. 2016; 87: 2527–32. DOI: 10.1212/WNL.0000000000003428
  31. Табеева Г.Р. Головная боль: Руководство для врачей. 2-е изд., перераб. и доп. М.: ГЭОТАР-Медиа; 2018. [Tabeeva G.R. Headache: Guide for doctors. 2nd ed., reprint. and add. Moscow: GEOTAR-Media; 2018 (in Russ.).
  32. Табеева Г.Р. Головная боль. М.: ГЭОТАР-Медиа; 2020. https://www.rosmedlib.ru/book/ISBN 9785970458648.html (дата обращения 10.11.2020) [Tabeeva G.R. Headache. Moscow: GEOTAR-Media; 2020 (in Russ.). https://www.rosmedlib.ru/book/ISBN9785970458648.html (accessed 10.11.2020)
  33. Ramadan N.M. Headache caused by raised intracranial pressure and intracranial hypotension. Curr. Opin. Neurol. 1996; 9: 214–8. DOI: 10.1097/00019052- 199606000-00011 39. Lipton R.B., Lowenkopf T., Bajwa Z.H., Leckie R.S., Ribeiro S., Newman L.C., Greenberg M.A. Cardiac cephalgia: a treatable form of exertional headache. Neurology. 1997; 49: 813–6. DOI: 10.1212/wnl.49.3.813
  34. Bini A., Evangelista A., Castellini P., Lambru G., Ferrante T., Manzoni G.C., Torelli P. Cardiac cephalgia. J. Headache Pain. 2009; 10: 3–9. DOI: 10.1007/s10194-008-0087-x
  35. Sacco S., Ripa P., Grassi D., Pistoia F., Ornello R., Carolei A. et al. Peripheral vascular dysfunction in migraine: a review. J. Head. Pain. 2013; 14: 80. DOI: 10.1186/1129-2377-14-80
  36. Butt J.H., Franzmann U., Kruuse C. Endothelial function in migraine with aura – a systematic review. Headache. 2015; 55: 35–54. DOI: 10.1111/head.12494
  37. Rambarat C., Elgendy I., Johnson B., Reis S.E., Thompson D.V., Sharaf B.L. et al. Migraine headache and long-term cardiovascular outcomes: an extended follow-up of the women’s ischemia syndrome evaluation. Am. J. Med. 2017; 130: 738–43. DOI: 10.1016/j.amjmed.2016.12.028
  38. Tietjen G.E., Khubchandani J. Vascular biomarkers in migraine. Cephalalgia. 2015; 35: 95–117. DOI: 10.1177/0333102414544976 45. Tietjen G.E., Collins S.A. Hypercoagulability and migraine. Headache. 2018; 58: 173–83. DOI: 10.1111/head.13044
  39. Iljazi A., Ayata C., Ashina M., Hougaard A. The role of endothelin in the pathophysiology of migraine – a systematic review. Curr. Pain Head. Rep. 2018; 22: 27. DOI: 10.1007/s11916-018-0682-8
  40. Kurth T. Migraine a marker of vascular health? Cephalalgia. 2013; 33: 226–7. DOI: 10.1177/0333102412472074
  41. Winsvold B.S., Bettella F., Witoelar A., Anttila V., Gormley P., Kurth T. et al. Shared genetic risk between migraine and coronary artery disease: a genome-wide analysis of common variants. PLoS One. 2017; 12: e0185663. DOI: 10.1371/journal.pone.0185663
  42. Winsvold B.S., Nelson C.P., Malik R., Gormley P., Anttila V., Vander Heiden J. et al. Genetic analysis for a shared biological basis between migraine and coronary artery disease. Neurol. Gen. 2015; 1: e10. DOI: 10.1212/nxg.0000000000000010
  43. Malik R., Freilinger T., Winsvold B.S., Anttila V., Vander Heiden J., Traylor M. et al. Shared genetic basis for migraine and ischemic stroke: a genome-wide analysis of common variants. Neurology. 2015; 84: 2132–45. DOI: 10.1212/wnl.0000000000001606
  44. Pickrell J.K., Berisa T., Liu J.Z., Segurel L., Tung J.Y., Hinds D.A. Detection and interpretation of shared genetic influences on 42 human traits. Nat. Gen. 2016; 48: 709–17. DOI: 10.1038/ng.3570
  45. Azimova J.E., Klimov E.A., Skorobogatykh K.V., Sergeev A.V., Kokaeva Z.G., Tabeeva G.R. Hemiplegic migraine. Medical Genetics. 2013; 12 (4): 3–7 (in Russ.).
  46. Ruff R.L., Ruff S.S., Wang X.-F. Headaches among operation iraqi freedom/operation enduring freedom veterans with mild traumatic brain injury associated with exposures to explosions. J. Rehabil. Res. Dev. 2008; 45 (7): 941–52. DOI: 10.1682/JRRD.2008.02.0028
  47. Filatova E.G., Osipova V.V., Tabeeva G.R., Parfenov V.A., Ekusheva E.V., Azimova Yu.E. et al. Diagnosis and treatment of migraines: recommendations of Russian experts. Neurology, Neuropsychiatry, Psychosomatics. 2020; 12 (4): 4–14 (in Russ.). DOI: 10.14412/2074-2711-2020-4-4-14
  48. Shumilina M.V., Buziashvili Yu.I. Disorders of venous cerebral circulation in patients with cardiovascular diseases. Clinical Physiology of Circulation. 2004; 2: 44–53 (in Russ.).
  49. Bockeria L.A., Buziashvili Yu.I., Shumilina M.V. Disorders of venous cerebral circulation in patients with cardiovascular pathology (headache, ischemia, arteriosclerosis). Moscow; 2003 (in Russ.).
  50. Gorbunova E.V., Shumilina M.V. MPP defect and cephalgic syndrome. Clinical Physiology of Circulation. 2009; 2: 24–30 (in Russ.).

About Authors

  • Ekaterina V. Emets, Postgraduate of Chair of Cardiology and Functional Diagnostics, Doctor of Functional Diagnostics; ORCID
  • Margarita V. Shumilina, Dr. Med. Sc., Professor of Chair of Cardiology and Functional Diagnostics, Head of Group of Ultrasound Diagnostics of Cardiovascular and Organ Pathology; ORCID

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