Clinical Physiology of Circulation

Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery


Analysis of correlations of heart rate variability in patientswith arterial hypertension

Authors: A.P. Spitsin

Company:
Kirov State Medical University, Ministry of Health of the Russian Federation, ul. Karla Marksa, 112, Kirov, 610998, Russian Federation

E-mail: Сведения доступны для зарегистрированных пользователей.

DOI: https://doi.org/10.24022/1814-6910-2017-14-3-146-151

UDC: 616.12-008.331.1-008.318

Link: Clinical Physiology of Blood Circulaiton. 2017; 14 (3): 146-151

Quote as: Spitsin A.P. Analysis of correlations of heart rate variability in patients with arterial hypertension. Klinicheskaya Fiziologiya Krovoobrashcheniya (Clinical Physiology of Circulation, Russian journal). 2017; 14 (3): 146–51 (in Russ.). DOI: 10.24022/1814-6910-2017-14-3-146-151

Received / Accepted:  19.04.2017/17.05.2017

Full text:  

Abstract

Objective: to study dependencies between basic and variable, temporary and spectral indicators of variability of heart rate in practically healthy persons and patients with arterial hypertension.
Material and methods. 19 males were studied. Their age was between 36 and 60 years. That was a basic group. The median age was 49.9 ± 1.7 years. The control group included 37 males of comparable ages (49.2 ± 1.3 years). For the analysis of variability of heart rates certain parameters were used. The above parameters were recommended by the Expert Committee of the European Society of Cardiologists and the North American Society of Stimulation and Electrophysiology. Correlative analyses of connections between the indicators of distribution and wave structure of cardiac intervals as well as connections between the indicators of hemodynamics and variability of heart rate.
Results. Unlike practically healthy persons, patients with arterial hypertension lacked correlative connections between systolic arterial pressure, diastolic arterial pressure and indicators of variability of heart rate. The patients with arterial hypertension showed significant decrease of activity of parasympatic part of the vegetative nervous system (RMSSD and particularly pNN50) and increase of activity of central contour of regulation (increase of VLF up to 49.34±3.42%). Quantity and quality of correlative connections in both statistic areas and spectral areas of cardiointervalograms and spectral areas of the vegetative nervous system changed in patients with arterial hypertension. If the practically healthy persons had high rates of correlation (r=0.87, p=0.0000 and r=0.77, p=0.0000 relatively) between SDNN and indicators of low frequency spectrum (VLF и LF), patients with arterial hypertension had LF r=0.65, p=0.002, and with VLF and there was no reliable connections (r=0.42, p=0.06).
Conclusion. Unlike practically healthy persons, the patients with arterial hypertension lacked reliable correlations between systolic atrial pressure, diastolic atrial pressure and indicators of variability of heart rates as well as changes of quantity and quality correlative connections in statistic areas of cardiointervalograms and spectral components of variability of heart rate.

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About Authors

Spitsin Anatoliy Pavlovich, Dr. Med. Sc., Professor, Chief of Chair of Pathophysiology; orcid.org/0000-0002-0942-6361

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