Clinical Physiology of Circulation

Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery


Методы антикоагуляции при проведении заместительной почечной терапии у больных с полиорганной недостаточностью и высоким риском развития кровотечения после операций на сердце и сосудах

Link: Clinical Physiology of Blood Circulaiton. 2005; (): -

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Abstract

We analyzed the results of 114 procedures of renal replacement therapy (RRT) in 55 patients with POF syndrome and high risk of bleeding in early postoperative period after open-heart surgery. We studied different methods of coagulation depending on initial degree of coagulopathy, thrombocytopenia and anemia in 5 groups of patients: without the use of systemic anticoagulation, with the use of modified extracorporeal circuit, with the use of systemic anticoagulation with heparin (3-5 U/kg/hour), lowmolecular heparins (0,05 ml/10 kg) and regional anticoagulation with heparin and protamine sulfate (1:1). We revealed the feasibility and the usefulness of the use of all methods of anticoagulation during RRT on the condition of differentiated approach and justified choice of methods in patients with high risk of bleeding after cardiac surgery

References

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