Clinical Physiology of Circulation

Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery


The current state of the headache problem

Authors: Mizgireva S.I., Shumilina M.V

DOI: https://doi.org/10.24022/1814-6910-2025-22-3-249-260

UDC: 616.831-009.7

Link: Clinical Physiology of Blood Circulaiton. 2025; 22 (3): 249-260

Quote as: Mizgireva S.I., Shumilina M.V. The current state of the headache problem. Clinical Physiology of Сirculation. 2025; 22 (3): 249–260 (in Russ.). DOI: 10.24022/1814-6910-2025-22-3-249-260

Received / Accepted:  25.07.2025 / 31.07.2025

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Abstract

Headache is one of the most common problems in the modern world. Assessment of the clinic and prognosis of cephalgic syndrome, including those associated with vascular pathology, is difficult, and the data on its diagnosis are currently contradictory. This review analyzes domestic and foreign publications reflecting the relationship of cephalalgia with vascular pathology, as well as the role of ultrasound duplex vascular scanning in the diagnosis of primary and secondary forms of headache. In addition to proven arterial pathologies as causes of cephalgic syndrome, many of the most common types of conditionally primary headaches (migraine, tension-type, etc.) and some types of secondary headaches (for example, with increased blood pressure) are based on disorders of cerebral venous outflow. The causes of its violation may be structural abnormalities of the intra- and extracranial (brachiocephalic) venous system, venous-arterial imbalance, musculofascial compression of the jugular veins, compression of the jugular veins by the styloid complex. An unobvious cause of headache may be throracic outlet syndrome (TOS) – its arterial and venous forms.

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