Clinical Physiology of Circulation

Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery


Ethiopathogenesis and immune status in the genesis of intraandpostoperative complications in patients with severe formsof coronary artery disease

Authors: I.A. Andrievskikh, S.I. Andrievskikh, M.O. Boldyreva, E.B. Milievskaya

Company:
Federal Center for Cardiovascular Surgery, Ministry of Health of the Russian Federation, prospekt Geroya Rossii Rodionova E.N., 2, Chelyabinsk, 454003, Russian Federation

E-mail: Сведения доступны для зарегистрированных пользователей.

DOI: https://doi.org/10.24022/1814-6910-2019-16-3-183-191

UDC: 616.12-005.4-089.166/.168.1-06

Link: Clinical Physiology of Blood Circulaiton. 2019; 16 (3): 183-191

Quote as: Andrievskikh I.A., Andrievskikh S.I., Boldyreva M.O., Milievskaya E.B. Ethiopathogenesis and immune status in the genesis of intra- and postoperative complications in patients with severe forms of coronary artery disease. Clinical Physiology of Circulation. 2019; 16 (3): 183–91 (in Russ.). DOI: 10.24022/1814-6910-2019-16-3-183-191

Received / Accepted:  01.07.2019/16.07.2019

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Abstract

Objective. To study the features of etiopathogenesis, immune status and the possibility of its correction in the preoperative period in patients with complicated forms of ischemic heart disease.

Material and methods. We have studed 100 patients with complicated forms of coronary artery disease, preparing for cardiac surgery in cardiopulmonary bypass. We specified combinations of etiopathogenetic factors. Identified features of the immune status of these patients.

Results. In the preoperative period, 50 of them underwent a personalized immunocorrection, which allowed, unlike the other 50 patients in this category, to significantly reduce the number of intra- and postoperative complications.

Conclusion. It has been proven that these pathogenetic approaches and immunocorrection in the complex treatment of surgical patients with complicated forms of ischemic heart disease, can significantly reduce the risk of developing intraand postoperative complications.

About Authors

  • Igor' A. Andrievskikh, Dr. Med. Sc., Professor, Cardiovascular Surgeon; orcid.org/0000-0003-2964-7353
  • Stanislav I. Andrievskikh, Cand. Med. Sc., Cardiovascular Surgeon, Head of Cardiac Surgeon Department № 1; orcid.org/0000-0002-3508-1504
  • Mariya O. Boldyreva, Cand. Med. Sc., Cardiologist; orcid.org/0000-0002-2016-9378
  • Elena B. Milievskaya, Dr. Med. Sc., Deputy Head of Scientific and Organizational Department, Bakoulev National Medical Research Center, Ministry of Health of the Russian Federation; orcid.org/0000-0001-9340-4212

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