Clinical Physiology of Circulation

Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery


Диагностика критических волемических нарушений у раненых на основе физико-математического моделирования реологических и гидромеханических процессов системы кровообращения

Link: Clinical Physiology of Blood Circulaiton. 2007; (): -

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Abstract

Executed theoretical and experimental researches in area of wound ballistics have allowed to elaborate a medical multifunction hardware-software complex «Phoenix», intended to determine the degree of gravity of gunshot injury and dynamic diagnosis of the biological objects state. The obtained outcomes of experimental researches have demonstrated, that the mechanism of damage of tissues at fire wounds has very composite nature and includes not only direct action injuring projectile, but also initiation of a number of physical phenomena leading to high-gravity hydrodynamic impact on heart and large veins, and also to considerable damages of tissues on the distance from wound channel with occurrence of free radicals initiating the pathological stage, influencing on development of a traumatic shock. Being elaborated for diagnosis of states pertaining to shock, the module of an intensive therapy has allowed to calculate values of productive activity of the left-hand and dextral ventricles of heart, value of a general peripheric resistance of vessels of large and small circles of blood circulation, and also dynamics of change of quadrant of an exocellular liquid, and the relative value of quadrant of a vascular liquid authentically characterizes a volume of a hemorrhage. All the above was based on using the invasively obtained parameters of values of arterial pressure and pulse rate. The dynamic monitoring of these parameters immediately describes a condition of an injured man and efficiency of antishock measures in real-time mode

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