Clinical Physiology of Circulation

Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery


Recurrent coronary stent thrombosis

Authors: Gitel’zon D.G., Faibushevich A.G., Gitel’zon E.A., Vasiliev A.E., Danishian K.I.

Company:
1 National Medical Research Center for Hematology, Moscow, Russian Federation
2 Peoples’ Friendship University of Russia, Moscow, Russian Federation

E-mail: Сведения доступны для зарегистрированных пользователей.

DOI: https://doi.org/10.24022/1814-6910-2022-19-3-197-200

UDC: 616.123.3-005.6

Link: Clinical Physiology of Blood Circulaiton. 2022; 3 (19): 197-200

Quote as: Gitel’zon D.G., Faibushevich A.G., Gitel’zon E.A., Vasiliev A.E., Danishian K.I. Recurrent coronary stent thrombosis. Clinical Physiology of Circulation. 2022; 19 (3): 197–200 (in Russ.). DOI: 10.24022/1814-6910-2022-19-3-197-200

Received / Accepted:  21.01.2022 / 10.09.2022

Download
Full text:  

Abstract

The review discusses the problem of recurrent coronary stent thrombosis development. The study of prevalence and search for risk factors of this life-threatening complication continues. Intravascular imaging, thin stent struts and more effective antiplatelet agents significantly reduced the risk of thrombotic complications after coronary artery stenting. Despite the significant progress made in this area, there are still many unresolved issues that need to be addressed in future research.

References

  1. Bangalore S., Toklu B., Patel N., Feit F., Stone G.W. Newer-generation ultrathin strut drug-eluting stents versus older second-generation thicker strut drug-eluting stents for coronary artery disease. Circulation. 2018; 138: 2216–26. DOI: 10.1161/CIRCULATIONAHA.118.034456
  2. Van Werkum J.W., Heestermans A.A.C.M., de Korte F.I., Kelder J.C., Suttorp M.-J., Rensing B.J.W.M. et al. Long-term clinical outcome after a first angiographically confirmed coronary stent thrombosis: an analysis of 431 cases. Circulation. 2009; 119: 828–34. DOI: 10.1161/CIRCULATIONAHA.108.799403
  3. Chechi T., Vecchio S., Vittori G., Giuliani G., Lilli A., Spaziani G. et al. ST-segment elevation myocardial infarction due to early and late stent thrombosis a new group of high-risk patients. J. Am. Coll. Cardiol. 2008; 51: 2396–402. DOI: 10.1016/j.jacc.2008.01.070
  4. Armstrong E.J., Sab S., Singh G.D., Lim W., Yeo K.-K., Waldo S.W. et al. Predictors and outcomes of recurrent stent thrombosis: results from a multicenter registry. JACC Cardiovasc. Interv. 2014; 7: 1105–13. DOI: 10.1016/j.jcin.2014.05.017
  5. Enomoto S., Kuramitsu S., Shinozaki T., Ohya M., Otake H., Yamanaka F. et al. Risk factors and outcomes of recurrent drug-eluting stent thrombosis: insights from the REAL-ST registry. J. Am. Heart Assoc. 2021; 10: e018972. DOI: 10.1161/JAHA.120.018972
  6. Kim M.C., Kim I.S., Jeong M.H., Sim D.S., Hong Y.J., Kim J.H. et al. Incidence of cardiac death and recurrent stent thrombosis after treatment for angiographically confirmed stent thrombosis. J. Cardiol. 2019; 74: 267–72. DOI: 10.1016/j.jjcc.2019.02.019
  7. Lemesle G., Sudre A., Modine T., Delhaye C., Rosey G., Gourlay T. et al. High incidence of recurrent in stent thrombosis after successful treatment of a first in stent thrombosis. Catheter. Cardiovasc. Interv. 2008; 72: 470–8. DOI: 10.1002/ccd.21709
  8. Choi S.-Y., Witzenbichler B., Maehara A., Lansky A.J., Guagliumi G., Brodie B. et al. Intravascular ultrasound findings of early stent thrombosis after primary percutaneous intervention in acute myocardial infarction: a Harmonizing Outcomes with Revascularization and Stents in Acute Myocardial Infarction (HORIZONSAMI) substudy. Circ. Cardiovasc. Interv. 2011; 4: 239–47. DOI: 10.1161/CIRCINTERVENTIONS. 110.959791
  9. Zhang J., Gao X., Kan J., Ge Z., Han L., Lu S. et al. Intravascular ultrasound versus angiography-guided drug-eluting stent implantation: the ULTIMATE trial. J. Am. Coll. Cardiol. 2018; 72: 3126–37. DOI: 10.1016/j.jacc.2018.09.013
  10. Mentias A., Sarrazin M.V., Saad M., Panaich S., Kapadia S., Horwitz P.A. et al. Long-term outcomes of coronary stenting with and without use of intravascular ultrasound. JACC Cardiovasc. Interv. 2020; 13: 1880–90. DOI: 10.1016/j.jcin.2020.04.052
  11. Гительзон Д.Г., Файбушевич А.Г., Максимкин Д.А., Веретник Г.И., Васильев А.Э., Гительзон Е.А., Данишян К.И. Контроль агрегации тромбоцитов в профилактике тромбоза коронарных стентов. Вестник Национального медико-хирургического центра им. Н.И. Пирогова. 2019; 14 (4): 131–4. DOI: 10.25881/BPNMSC.2020.60.92.026
  12. Пряхин И.С., Мурашко С.С., Бернс С.А., Пасечник И.Н., Арсеньева Н.В., Дьякова Н.П. и др. Агрегация тромбоцитов как маркер эффективности и безопасности антиагрегантной терапии у пациентов с ишемической болезнью сердца. Кремлевская медицина. Клинический вестник. 2020; 1: 64–71. DOI: 10.26269/hb8d-qg49
  13. Spinthakis N., Farag M., Rocca B., Gorog D.A. More, more, more: reducing thrombosis in acute coronary syndromes beyond dual antiplatelet therapy-current data and future directions. J. Am. Heart Assoc. 2018; 7: e007754. DOI: 10.1161/JAHA.117.007754
  14. Gibson C.M., Chakrabarti A.K., Mega J., Bode C., Bassand J.-P., Verheugt F.W.A. et al. Reduction of stent thrombosis in patients with acute coronary syndromes treated with rivaroxaban in ATLAS-ACS 2 TIMI 51. J. Am. Coll. Cardiol. 2013; 62: 286–90. DOI: 10.1016/j.jacc.2013.03.041
  15. Pereira N.L., Farkouh M.E., So D., Lennon R., Geller N., Mathew V. et al. Effect of genotype-guided oral P2Y12 inhibitor selection vs conventional clopidogrel therapy on ischemic outcomes after percutaneous coronary intervention: the TAILOR-PCI randomized clinical trial. JAMA. 2020; 324: 761–71. DOI: 10.1001/jama.2020.12443
****
  1. Bangalore S., Toklu B., Patel N., Feit F., Stone G.W. Newer-generation ultrathin strut drug-eluting stents versus older second-generation thicker strut drug-eluting stents for coronary artery disease. Circulation. 2018; 138: 2216–26. DOI: 10.1161/CIRCULATIONAHA.118.034456
  2. Van Werkum J.W., Heestermans A.A.C.M., de Korte F.I., Kelder J.C., Suttorp M.-J., Rensing B.J.W.M. et al. Long-term clinical outcome after a first angiographically confirmed coronary stent thrombosis: an analysis of 431 cases. Circulation. 2009; 119: 828–34. DOI: 10.1161/CIRCULATIONAHA.108.799403
  3. Chechi T., Vecchio S., Vittori G., Giuliani G., Lilli A., Spaziani G. et al. ST-segment elevation myocardial infarction due to early and late stent thrombosis a new group of high-risk patients. J. Am. Coll. Cardiol. 2008; 51: 2396–402. DOI: 10.1016/j.jacc.2008.01.070
  4. Armstrong E.J., Sab S., Singh G.D., Lim W., Yeo K.-K., Waldo S.W. et al. Predictors and outcomes of recurrent stent thrombosis: results from a multicenter registry. JACC Cardiovasc. Interv. 2014; 7: 1105–13. DOI: 10.1016/j.jcin.2014.05.017
  5. Enomoto S., Kuramitsu S., Shinozaki T., Ohya M., Otake H., Yamanaka F. et al. Risk factors and outcomes of recurrent drug-eluting stent thrombosis: insights from the REAL-ST registry. J. Am. Heart Assoc. 2021; 10: e018972. DOI: 10.1161/JAHA.120.018972
  6. Kim M.C., Kim I.S., Jeong M.H., Sim D.S., Hong Y.J., Kim J.H. et al. Incidence of cardiac death and recurrent stent thrombosis after treatment for angiographically confirmed stent thrombosis. J. Cardiol. 2019; 74: 267–72. DOI: 10.1016/j.jjcc.2019.02.019
  7. Lemesle G., Sudre A., Modine T., Delhaye C., Rosey G., Gourlay T. et al. High incidence of recurrent in stent thrombosis after successful treatment of a first in stent thrombosis. Catheter. Cardiovasc. Interv. 2008; 72: 470–8. DOI: 10.1002/ccd.21709
  8. Choi S.-Y., Witzenbichler B., Maehara A., Lansky A.J., Guagliumi G., Brodie B. et al. Intravascular ultrasound findings of early stent thrombosis after primary percutaneous intervention in acute myocardial infarction: a Harmonizing Outcomes with Revascularization and Stents in Acute Myocardial Infarction (HORIZONSAMI) substudy. Circ. Cardiovasc. Interv. 2011; 4: 239–47. DOI: 10.1161/CIRCINTERVENTIONS. 110.959791
  9. Zhang J., Gao X., Kan J., Ge Z., Han L., Lu S. et al. Intravascular ultrasound versus angiography-guided drug-eluting stent implantation: the ULTIMATE trial. J. Am. Coll. Cardiol. 2018; 72: 3126–37. DOI: 10.1016/j.jacc.2018.09.013
  10. Mentias A., Sarrazin M.V., Saad M., Panaich S., Kapadia S., Horwitz P.A. et al. Long-term outcomes of coronary stenting with and without use of intravascular ultrasound. JACC Cardiovasc. Interv. 2020; 13: 1880–90. DOI: 10.1016/j.jcin.2020.04.052
  11. Gitelson D.G., Faibushevich A.G., Maximkin D.A., Veretnik G.I., Vasiliev A.E., Gitelson E.A., Danishian K.I. Coronary stent thrombosis prevention by platelet aggregation test. Bulletin of Pirogov National Medical & Surgical Center. 2019; 4 (14): 131–4 (in Russ.). DOI: 10.25881/BPNMSC.2020.60.92.026
  12. Pryakhin I.S., Murashko S.S., Berns S.A., Pasechnik I.N., Arsen'eva N.V., D'yakova N.P. et al. Aggregation of throbocytes as a marker of efficiency and safety of antiplatelet therapy in patient with coronary heart disease. Kremlin Medicine Journal. 2020; 1: 64–71. DOI: 10.26269/hb8d-qg49
  13. Spinthakis N., Farag M., Rocca B., Gorog D.A. More, more, more: reducing thrombosis in acute coronary syndromes beyond dual antiplatelet therapy-current data and future directions. J. Am. Heart Assoc. 2018; 7: e007754. DOI: 10.1161/JAHA.117.007754
  14. Gibson C.M., Chakrabarti A.K., Mega J., Bode C., Bassand J.-P., Verheugt F.W.A. et al. Reduction of stent thrombosis in patients with acute coronary syndromes treated with rivaroxaban in ATLAS-ACS 2 TIMI 51. J. Am. Coll. Cardiol. 2013; 62: 286–90. DOI: 10.1016/j.jacc.2013.03.041
  15. Pereira N.L., Farkouh M.E., So D., Lennon R., Geller N., Mathew V. et al. Effect of genotype-guided oral P2Y12 inhibitor selection vs conventional clopidogrel therapy on ischemic outcomes after percutaneous coronary intervention: the TAILOR-PCI randomized clinical trial. JAMA. 2020; 324: 761–71. DOI: 10.1001/jama.2020.12443

About Authors

  • Daniel G. Gitel’zon, Cand. Med. Sci., Interventional Radiologist; ORCID
  • Aleksandr G. Faibushevich, Cand. Med. Sci., Chief of Chair; ORCID
  • Ekaterina A. Gitel’zon, Cand. Med. Sci., Assistant Professor; ORCID
  • Aleksandr E. Vasiliev, Cand. Med. Sci.; ORCID
  • Karen I. Danishian, Dr. Med. Sci., Head of Department; ORCID

 If you found mistakes, select text and press Alt+A