Clinical Physiology of Circulation

Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery


Anatomy and function of the left atrium: from diagnostics to clinical practice

Authors: Koksheneva I.V., Kaplenko L.I.

Company:
Bakoulev National Medical Research Center for Cardiovascular Surgery, Moscow, Russian Federation

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DOI: https://doi.org/10.24022/1814-6910-2022-19-4-302-313

UDC: 616.125.2-091

Link: Clinical Physiology of Blood Circulaiton. 2022; 4 (19): 302-313

Quote as: Koksheneva I.V., Kaplenko L.I. Anatomy and function of the left atrium: from diagnostics to clinical practice. Clinical Physiology of Circulation. 2022; 19 (4): 302–13 (in Russ.). DOI: 10.24022/1814-6910-2022-19-4-302-313

Received / Accepted:  24.10.2022 / 16.12.2022

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Abstract

Today, there is a reassessment of the role of the left atrium (LA) in the pathogenesis of symptoms and the impact on the prognosis of cardiovascular diseases. There is extensive evidence that structural and functional abnormalities of the LA myocardium, which are present in many cardiovascular diseases, are a powerful prognostic indicator. According to modern concepts, the left atrium in the physiology of systemic hemodynamics has gradually moved from a passive chamber to a central and active element of general hemodynamics. The anatomical, mechanical, hemodynamic, electrophysiological and rheological role of LА has been proven.
The article presents an overview of research on the anatomy, physiology, features of remodeling and dysfunction of the left atrium, presents modern diagnostic approaches to assessing the geometry and function of the left atrium. The information content and predictive accuracy of the assessment of the geometry and mechanical function of the LA in predicting negative cardiovascular outcomes are considered.
In the future, studies on the problem of left atrial dysfunction will improve diagnosis, create the basis for a deeper understanding of the mechanisms underlying LA dysfunction and the development of effective treatment methods.

About Authors

  • Inna V. Koksheneva, Dr. Med. Sci., Senior Researcher; ORCID
  • Lydia I. Kaplenko, Postgraduate; ORCID

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