Clinical Physiology of Circulation

Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery


The importance of assessing the mechanical function of the left atrial in patients with mitral regurgitation

Authors: Koksheneva I.V., Kaplenko L.I., Turakhonov T.K., Zhertovskaya E.V., Ambatiello S.G.

Company:
Bakoulev National Medical Research Center for Cardiovascular Surgery, Moscow, Russian Federation

E-mail: Сведения доступны для зарегистрированных пользователей.

DOI: https://doi.org/10.24022/1814-6910-2023-20-3-213-220

UDC: 616.125.2-008.17

Link: Clinical Physiology of Blood Circulaiton. 2023; 3 (20): 213-220

Quote as: Koksheneva I.V., Kaplenko L.I., Turakhonov T.K., Zhertovskaya E.V., Ambatiello S.G. The importance of assessing the mechanical function of the left atrial in patients with mitral regurgitation. Clinical Physiology of Circulation. 2023; 20 (3): 213–20 (in Russ.). DOI: 10.24022/1814-6910-2023-20-3-213-220

Received / Accepted:  21.07.2023 / 04.09.2023

Download
Full text:  

Abstract

The left atrium (LA) is a key element in the pathophysiology of several cardiovascular diseases, as it plays an active role in the development and progression of heart failure symptoms. Mitral valve insufficiency leads to LA volume overload and stagnation in the pulmonary circulation. Chronic LA volume overload can lead to significant LA remodeling characterized by dilatation, atrial myocardial fibrosis, decreased elasticity/increased stiffness, and impaired mechanical function, which has a direct impact on pulmonary hemodynamics.

Strain and Strain Rate parameters allow assessment of atrial phasic function (reservoir, conduction and contraction phases) throughout the cardiac cycle. The Strain and Strain Rate parameters of the left atrium are an important tool in assessing the severity of left atrium myocardial fibrosis, predicting the development of heart failure, determining the timing of surgical correction of mitral disease and predicting outcomes.

The article provides a review of studies regarding the clinical and prognostic use of left atrium Strain and Strain Rate parameters in patients with mitral regurgitation.

About Authors

  • Inna V. Koksheneva, Dr. Med. Sci., Senior Researcher; ORCID
  • Lidiya I. Kaplenko, Postgraduate; ORCID
  • Temur K. Turakhonov, Cand. Med. Sci., Cardiologist; ORCID
  • Ekaterina V. Zhertovskaya, Junior Researcher; ORCID
  • Sergey G. Ambatiello, Dr. Med. Sci., Leading Researcher; ORCID

 If you found mistakes, select text and press Alt+A