Clinical Physiology of Circulation

ISSN 1814-6910 (Print)
ISSN 2410-9134 (Online)

 

Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery


Issue's catalogue ➤ КФК. 2023; 20 (3): 203-320 ➤ Методы определения и мониторирования биомаркеров состояния кровоснабжения тканей на экспериментальных моделях и при кожно-пластических операциях

Methods for determining and monitoring biomarkers of the state of blood supply to tissue in experimental models and during skin-plastic surgery

Authors: Bagyan A.R., Malinin A.A.

Company:
Bakoulev National Medical Research Center for Cardiovascular Surgery, Moscow, Russian Federation

E-mail: Сведения доступны для зарегистрированных пользователей.

DOI: https://doi.org/10.24022/1814-6910-2023-20-3-242-253

UDC: 612.816.4-092.9

Link: Clinical Physiology of Blood Circulaiton. 2023; 3 (20): 242-253

Quote as: Bagyan A.R., Malinin A.A. Methods for determining and monitoring biomarkers of the state of blood supply to tissue in experimental models and during skin-plastic surgery. Clinical Physiology of Circulation. 2023; 20 (3): 242–53 (in Russ.). DOI: 10.24022/1814-6910-2023-20-3-242-253

Keywords:  skin plastic surgery shave-therapy surgery skin autotransplantation plastic surgery with local tissues determination of tissue blood supply tissue viability

Received / Accepted:  04.08.2023 / 13.09.2023

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Abstract

The review is devoted to methods for determining the blood supply to various types of skin flaps that are used in skin plastic surgery. To improve treatment results, methods of constant monitoring of the state of their blood supply are used, as the main factor in their viability. They must have such important characteristics as simplicity, accessibility, reproducibility, reliability and the possibility of monitoring. The review analyzes the main factors of the study and new devices based on nanotechnology, biosensors for determining various biomarkers by wirelessly monitoring the state of blood supply to skin flaps. Modern technological methods for monitoring biomarkers with wearable devices that, based on microsensors, transmit research results in real time are presented. Detection of tissue ischemia of the skin flap allows treatment and avoidance of its death. The information presented in the review gives an idea of the current technological level of tissue viability monitoring devices. This will allow surgeons to choose the most appropriate method of monitoring the state of the autograft blood supply for a specific type of skin flap, which will make it possible to improve the results of the operation by timely changing treatment tactics.

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****
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About Authors

  • Arut R. Bagyan, Postgraduate; ORCID
  • Aleksandr A. Malinin, Dr. Med. Sci., Chief Researcher; ORCID

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