Clinical Physiology of Circulation

Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery


Transthoracic ultrasound assessment of biomechanical properties of the ascending aorta using tissue Doppler and speckle- tracking echocardiography: comparison of different postprocessing approaches

Authors: Golukhova E.Z., Pursanova D.M., Mironenko V.A., Mironenko M.Yu., Tkhashokova L.R.

Company:
Bakoulev National Medical Research Center for Cardiovascular Surgery, Moscow, Russian Federation

E-mail: Сведения доступны для зарегистрированных пользователей.

DOI: https://doi.org/10.24022/1814-6910-2023-20-4-353-361

UDC: 616.132.13-073.43

Link: Clinical Physiology of Blood Circulaiton. 2023; 4 (20): 353-361

Quote as: Golukhova E.Z., Pursanova D.M., Mironenko V.A., Mironenko M.Yu., Tkhashokova L.R. Transthoracic ultrasound assessment of biomechanical properties of the ascending aorta using tissue Doppler and speckle-tracking echocardiography: comparison of different postprocessing approaches. Clinical Physiology of Circulation. 2023; 20 (4): 353–61 (in Russ.). DOI: 10.24022/1814-6910-2023-20-4-353-361

Received / Accepted:  29.09.2023 / 20.11.2023

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Abstract

Objective. To develop the methodology of application of transthoracic ultrasound techniques – pulsed-wave tissue Doppler (TD) and speckle- tracking echocardiography (STE) – in the assessment of biomechanical properties of the ascending aortic (AA) wall in aneurysm and in the control group.

Material and methods. The study included 60 patients (37 men, 23 women) in two main groups – with AA aneurysm (ME diameter 55 [49; 58] mm) and controls (ME diameter 30 [28; 33] mm). Performing TD for evaluation of AA wall motion velocities (S, E and A) the reference volume was placed on six points – three on each – anterior and posterior wall. Performing STE for evaluation of local longitudinal strain, AA wall deformation was assessed using two starting points: 1) from aortic annulus; 2) from sinotubular junction.

Results. Analysis of TD results showed that the AA aneurysm is characterized by decrease in velocity parameters; of the six measurement points, all three velocities (S, E and A) differed significantly only at two points (p<0.03), with the most significant difference – at ~3 cm from the aortic annulus on anterior wall (p<0.003). Analysis of STE results showed that of the two post-processing approaches, the measurement starting from aortic annulus is optimal: the strain was significantly lower in AA aneurysm in three segments – anterior sinus, anterior AA and posterior AA (p < 0.01).

Conclusions. The comparative analysis showed that transthoracic ultrasonic evaluation of AA biomechanics should include following post- processing assessment: TD – on anterior AA wall at ~3 cm from aortic annulus, STE – starting from aortic annulus. Using these postprocessing approaches showed in patients with AA aneurysm, compared with the control group, significantly lower values for all velocity parameters at TD (p<0.03), as well as lower local longitudinal strain at STE in three segments – anterior sinus, anterior AA and posterior AA (p<0.01).

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About Authors

  • Elena Z. Golukhova, Dr. Med. Sci., Professor, Academician of RAS, Director; ORCID
  • Diana M. Pursanova, Dr. Med. Sci., Professor of Chair of Radiation Diagnostics, Senior Researcher; ORCID
  • Vladimir A. Mironenko, Dr. Med. Sci., Head of Department of Reconstructive Surgery and Aortic Root; ORCID
  • Marina Yu. Mironenko, Cand. Med. Sci., Head of Department of Ultrasound Diagnostics, Ultrasonic Diagnostician; ORCID
  • Luiza R. Tkhashokova, Postgraduate; ORCID

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