Clinical Physiology of Circulation

Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery


Hospital results of transcatheter implantation in patients with bicuspid aortic valve

Authors: Mkrtychev D.S., Komlev A.E., Kolegaev A.S., Lepilin P.M., Salichkin D.V., Kabardieva M.R., Imaev T.E.

Company:
National Medical Research Centre of Cardiology named after academician E.I. Chazov, Moscow, Russian Federation

E-mail: Сведения доступны для зарегистрированных пользователей.

DOI: https://doi.org/10.24022/1814-6910-2023-20S1-27-37

UDC: 616.126.52-089.844

Link: Clinical Physiology of Blood Circulaiton. 2023; Спецвыпуск (20): 27-37

Quote as: Mkrtychev D.S., Komlev A.E., Kolegaev A.S., Lepilin P.M., Salichkin D.V., Kabardieva M.R., Imaev T.E. Hospital results of transcatheter implantation in patients with bicuspid aortic valve. Clinical Physiology of Circulation. 2023; 20 (Special Issue 1): 27–37 (in Russ.). DOI: 10.24022/1814-6910-2023-20S1-27-37

Received / Accepted:  26.09.2023 / 06.11.2023

Download
Full text:  

Abstract

Objective. To compare hospital results of transcatheter implantation (TAVI) in patients with different types of aortic valve. 

Material and methods. The study included 104 patients who underwent TAVI using CoreValve Evolut R (Medtronic) and Acurate Neo2 (Boston Scientific) self-opening prostheses. The patients were divided into groups depending on the structure of the aortic valve: 49 patients with bicuspid aortic valve (BAV) were in the main group, 55 patients with tricuspid aortic valve (TAV) were in the control group. During the study, complications of TAVI, perioperative and hospital mortality, rhythm and conduction disorders, and the need for permanent pacemaker implantation were analyzed. Larger valves were implanted significantly more often than in the control group (12 (43%) vs. 7 (13%), p = 0.0021). Hemodynamic parameters improved significantly after surgery and did not differ statistically between the groups.

Conclusion. Hospital results obtained during the comparison of patients with different types of aortic valves demonstrate effectiveness and safety of TAVI in carefully picked patients with BAV. Complex clinical cases may require an aortic prosthesis with the possibility of repositioning due to the difficulties of achieving its optimal position in the fibrous ring due to severe calcification and the shape of the aortic valve itself.

About Authors

  • David S. Mkrtychev, Postgraduate, Cardiovascular Surgeon; ORCID
  • Aleksey E. Komlev, Cardiologist; ORCID
  • Aleksandr S. Kolegaev, Cand. Med. Sci., Senior Researcher, Cardiovascular Surgeon; ORCID
  • Petr M. Lepilin, Cand. Med. Sci., Senior Researcher, Cardiovascular Surgeon; ORCID
  • Dmitriy V. Salichkin, Cand. Med. Sci., Cardiovascular Surgeon; ORCID
  • Madina R. Kabardieva, Cand. Med. Sci., Cardiologist; ORCID
  • Timur E. Imaev, Dr. Med. Sci., Chief Researcher, Head of Laboratory; ORCID

 If you found mistakes, select text and press Alt+A