Clinical Physiology of Circulation

Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery


Local disturbance of main blood flow as a mechanism of failure of ischemic compensation in stenotic lesions of the vascular bed (based on the example of the coronary pool)

Authors: Bocharov A.V.1 2, Popov L.V.3, Savostyanov K.A.4

Company:
1 Central Clinical Hospital of St. Alexy Metropolitan of Moscow of the Moscow Patriarchate of the Russian Orthodox Church, Moscow, Russian Federation
2 Pirogov Russian National Research Medical University, Moscow, Russian Federation
3 National Medical and Surgical Center named after N.I. Pirogov, Moscow, Russian Federation
4 Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation

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DOI: https://doi.org/10.24022/1814-6910-2024-21-4-290-299

UDC: 616.132.2-007.271

Link: Clinical Physiology of Blood Circulaiton. 2024; 21 (4): 290-299

Quote as: Bocharov A.V., Popov L.V., Savostyanov K.A. Local disturbance of main blood flow as a mechanism of failure of ischemic compensation in stenotic lesions of the vascular bed (based on the example of the coronary pool). Clinical Physiology of Circulation. 2024; 21 (4): 290–299 (in Russ.). DOI: 10.24022/1814-6910-2024-21-4-290-299

Received / Accepted:  30.10.2024 / 20.11.2024

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Abstract

The basic models of hemodynamic disturbances are considered, namely: collateral circulation, competitive blood flow, critical stenosis model. The presented basic models of local hemodynamic disturbances, in our opinion, can explain the cause of local disturbances of the main blood flow with a significant impact of one factor or a combination of several factors of minor severity, such as insufficiency of collateral circulation, occurrence of competitive blood flow and stenotic lesion, which will lead to a significant decrease in the volumetric blood flow velocity in the distal bed.

About Authors

  • Aleksandr V. Bocharov, Dr. Med. Sci.; ORCID
  • Leonid V. Popov, Dr. Med. Sci., Professor; ORCID
  • Kirill A. Savostyanov, Cand. Med. Sci.; ORCID

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