Clinical Physiology of Circulation

Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery


Justification of clinically effective severity index of heart failure:comparison of sensitivity of ejection fraction and indexes of end volumes

Authors: D.Sh. Gazizova

Company:
Bakoulev National Medical Research Center for Cardiovascular Surgery, Ministry of Health of the Russian Federation, Rublevskoe shosse, 135, Moscow, 121552, Russian Federation

E-mail: Сведения доступны для зарегистрированных пользователей.

DOI: https://doi.org/10.24022/1814-6910-2019-16-3-209-216

UDC: 616.12-008.46-07

Link: Clinical Physiology of Blood Circulaiton. 2019; 16 (3): 209-216

Quote as: Gazizova D.Sh. Justification of clinically effective severity index of heart failure: comparison of sensitivity of ejection fraction and indexes of end volumes. Clinical Physiology of Circulation. 2019; 16 (3): 209–16 (in Russ.). DOI: 10.24022/1814-6910-2019-16-3-209-216

Received / Accepted:  08.07.2019/24.07.2019

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Abstract

Objective. To find sensitive clinically effective indicator of heart failure severity and to prove a possibility of its use in clinical practice.

Material and methods. 49 patients with dilated cardiomyopathy with complete monitor and computer control are include for the analysis. Patients were divided into 2 group for identification of sensitivity of ejection fraction and end volumes to severity of a heart failure. Patients with the cardiac index more average value for all examined patients are included to the first group, with the cardiac index less average value – to another.

Results. There was a significant difference in the definition of cardiac output: the average cardiac output in the groups compared to the average for all was higher and lower by 24%. At that time, ejection fraction changed little and did not reflect the change in heart function in patients with dilated cardiomyopathy. When analyzing the results of another similar our study and literature it was revealed that the decrease in ejection fraction in the group of patients with complications is due to an end systolic volume index increase. It is found that the change in the end volumes to a greater extent and more reliably than the ejection fraction reflects both the results of the operation and the complications.

Conclusion. The expediency of use of indexes of end volumes as indicators of a heart failure is proved.

About Authors

Dinara Sh. Gazizova, Dr. Med. Sc., Chief Researcher; orcid.org/0000-0002-2057-1789

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