Clinical Physiology of Circulation

Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery


Justification of clinically effective severity index of heart failure:comparison of sensitivity of ejection fraction and indexes of end volumes

Authors: D.Sh. Gazizova

Company:
Bakoulev National Medical Research Center for Cardiovascular Surgery, Ministry of Health of the Russian Federation, Rublevskoe shosse, 135, Moscow, 121552, Russian Federation

E-mail: Сведения доступны для зарегистрированных пользователей.

DOI: https://doi.org/10.24022/1814-6910-2019-16-3-209-216

UDC: 616.12-008.46-07

Link: Clinical Physiology of Blood Circulaiton. 2019; 16 (3): 209-216

Quote as: Gazizova D.Sh. Justification of clinically effective severity index of heart failure: comparison of sensitivity of ejection fraction and indexes of end volumes. Clinical Physiology of Circulation. 2019; 16 (3): 209–16 (in Russ.). DOI: 10.24022/1814-6910-2019-16-3-209-216

Received / Accepted:  08.07.2019/24.07.2019

Download
Full text:  

Abstract

Objective. To find sensitive clinically effective indicator of heart failure severity and to prove a possibility of its use in clinical practice.

Material and methods. 49 patients with dilated cardiomyopathy with complete monitor and computer control are include for the analysis. Patients were divided into 2 group for identification of sensitivity of ejection fraction and end volumes to severity of a heart failure. Patients with the cardiac index more average value for all examined patients are included to the first group, with the cardiac index less average value – to another.

Results. There was a significant difference in the definition of cardiac output: the average cardiac output in the groups compared to the average for all was higher and lower by 24%. At that time, ejection fraction changed little and did not reflect the change in heart function in patients with dilated cardiomyopathy. When analyzing the results of another similar our study and literature it was revealed that the decrease in ejection fraction in the group of patients with complications is due to an end systolic volume index increase. It is found that the change in the end volumes to a greater extent and more reliably than the ejection fraction reflects both the results of the operation and the complications.

Conclusion. The expediency of use of indexes of end volumes as indicators of a heart failure is proved.

References

  1. Рекомендации ESC по диагностике и лечению острой и хронической сердечной недостаточности 2016. Российский кардиологический журнал. 2017; 22 (1): 7 – 81. [2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Russian Journal of Cardiology. 2017; 22 (1): 7 – 81 (in Russ.).]
  2. 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: the task force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC). Developed with the special contribution of the Heart Failure Association (HFA) of the ESC. Eur. Heart J. 2016; 37 (27): 2129 – 200. DOI: 10.1002/ejhf.592
  3. Andronic A.A., Mihaila S., Cinteza M. Heart failure with mid-range ejection fraction – a new category of heart failure or still a gray zone. Maedica (Buchar). 2016; 11 (4): 320 – 4. PMCID: PMC5543525
  4. Shillcutt S.K., Chacon M.M., Brakke T.R., Roberts E.K., Schulte T.E., Markin N. Heart failure with preserved ejection fraction: a perioperative review. J. Cardiothorac. Vasc. Anesth. 2017; 31 (5): 1820 – 30. DOI: 10.1053/j.jvca.2017.06.009
  5. Gori M., Iacovoni A., Senni M. Haemodynamics of heart failure with preserved ejection fraction: a clinical perspective. Card. Fail. Rev. 2016; 2 (2): 102 – 5. DOI: 10.15420/cfr.2016:17:2
  6. Maciver D.H. The relative impact of circumferential and longitudinal shortening on left ventricular ejection fraction and stroke volume. Exp. Clin. Cardiol. 2012; 17: 5 – 11. PMCID: PMC3383360
  7. Kraigher-Krainer, Shah A.M., Gupt D.K. Impaired systolic function by strain imaging in heart failure with preserved ejection fraction. J. Am. Coll. Cardiol. 2014; 63: 447 – 56. DOI: 10.1016/j.jacc.2013.09.052
  8. Cikes M., Solomon S.D. Beyond ejection fraction: an integrative approach for assessment of cardiac structure and function in heart failure. Eur. Heart J. 2016; 37 (21): 1642 – 50. DOI: 10.1093/eurheartj/ehv510
  9. Бокерия Л.А., Лищук В.А., Газизова Д.Ш., Сазыкина Л.В., Соболев А.В., Махмудова А.Н. и др. Концепция регуляции сердечно-сосудистой системы – от управления функциями к согласованию возможностей. Часть 4. Анализ клинического материала. Клиническая физиология кровообращения. 2013; 1: 24 – 34. [Bockeria L.A., Lishchuk V.A., Gazizova D.Sh., Sazykina L.V., Sobolev A.V., Makhmudova A.N. et al. The concept of a regulation of cardiovascular system – from management functions to coordination opportunities. Part 4. Analysis of clinical material. Clinical Physiology of Circulation. 2013; 1: 24 – 34 (in Russ.).]
  10. Бокерия Л.А., Лищук В.А., Газизова Д.Ш., Сазыкина Л.В., Соболев А.В., Махмудова А.Н. и др. Концепция регуляции сердечно-сосудистой системы – от управления функциями к согласованию возможностей. Часть 5. Роль регуляции. Клиническая физиология кровообращения. 2013; 1: 34 – 44. [Bockeria L.A., Lishchuk V.A., Gazizova D.Sh., Sazykina L.V., Sobolev A.V., Makhmudova A.N. et al. The concept of a regulation of cardiovascular system – from management functions to coordination opportunities. Part 5. The role of regulation. Clinical Physiology of Circulation. 2013; 1: 34 – 44 (in Russ.).]
  11. Бокерия Л.А., Лищук В.А., Сокольская Н.О., Газизова Д.Ш., Сазыкина Л.В. Построение компьютерной модели кровообращения по данным комплексного эхокардиографического обследования больных с врожденными пороками сердца в раннем послеоперационном периоде. Сердечно-сосудистые заболевания. Бюллетень НЦССХ им. А.Н. Бакулева РАМН. 2004; 5 (2): 29 – 36. [Bockeria L.A., Lishchuk V.A., Sokol , skaya N.O., Gazizova D.Sh., Sazykina L.V. Creation of computer model of a circulation according to comprehensive echocardiographic examination of patients with congenital heart diseases in the early postoperative period. The Bulletin of Bakoulev Center. Cardiovascular Diseases. 2004; 5 (2): 29 – 36 (in Russ.).]
  12. Катамадзе Н.А., Кикнадзе М.П., Кистаури А.Г., Бегишвили Н.Н. Функции левого желудочка и ишемическая кардиомиопатия. Клиническая физиология кровообращения. 2005; 1: 45 – 52. [Katamadze N.A., Kiknadze M.P., Kistauri A.G., Begishvili N.N. Functions of a left ventricle and ischemic cardiomyopathy. Clinical Physiology of Circulation. 2005; 1: 45 – 52 (in Russ.).]
  13. Бокерия Л.А., Алшибая М.М., Мерзляков В.Ю., Сокольская Н.О., Копылова Н.С., Скрипник Е.В. Интраоперационная чреспищеводная экокардиография у больных с различными формами ишемической болезни сердца. Клиническая физиология кровообращения. 2016; 13 (3): 139 – 47. [Bockeria L.A., Alshibaya M.M., Merzlyakov V.Yu., Sokol , skaya N.O., Kopylova N.S., Skripnik E.V. An intraoperative transesophageal ecocardiography at patients with various forms of coronary heart disease. Clinical Physiology of Circulation. 2016; 13 (3): 139 – 47 (in Russ.).]
  14. Газизова Д.Ш. Клинико-физиологические представления о норме. Клиническая физиология кровообращения. 2005; 3: 49 – 60. [Gazizova D.Sh. Clinical-physiological ideas of norm. Clinical Physiology of Circulation. 2005; 3: 49 – 60 (in Russ.).]
  15. Бокерия Л.А., Шурупова И.В., Асланиди И.П., Никитина Т.Г., Иродова Н.Л., Авакова С.А. и др. Дилатационная кардиомиопатия: оценка перфузии и метаболизма миокарда по данным радионуклидных методов исследования. Клиническая физиология кровообращения. 2010; 2: 61 – 72. [Bockeria L.A., Shurupova I.V., Aslanidi I.P., Nikitina T.G., Irodova N.L., Avakova S.A. et al. Dilated cardiomiopatiya: assessment of perfusion and a metabolism of a myocardium according to radio nuclide methods of a research. Clinical Physiology of Circulation. 2010; 2: 61 – 72 (in Russ.).]

About Authors

Dinara Sh. Gazizova, Dr. Med. Sc., Chief Researcher; orcid.org/0000-0002-2057-1789

 If you found mistakes, select text and press Alt+A