Clinical Physiology of Circulation

ISSN 1814-6910 (Print)
ISSN 2410-9134 (Online)

 

Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery


Issue's catalogue ➤ КФК. 2019; 16 (3): 165-254 ➤ Особенности изменения гемодинамических характеристик магистрального и тканевого кровотока при патологической извитости внутренних сонных артерий по данным фазово-контрастной и перфузионной магнитно-резонансной томографии

Features of changes in the hemodynamic characteristics of the mainand tissue blood flow in the pathological tortuosity of the internal carotidarteries according to phase-contrast and perfusion magnetic resonance imaging

Authors: Yu.A. Stankevich 1, O.B. Bogomyakova 1, L.M. Vasil'kiv 1, A.A. Tulupov 1, 2

Company:
1 Institute International Tomography Center, Siberian Branch of the Russian Academy of Sciences, ul. Institutskaya, 3a, Novosibirsk, 630090, Russian Federation
2Novosibirsk State University, ul. Pirogova, 1, Novosibirsk, 630090, Russian Federation

E-mail: Сведения доступны для зарегистрированных пользователей.

DOI: https://doi.org/10.24022/1814-6910-2019-16-3-217-227

UDC: 616.133.3-007.5-073.756.8:612.15

Link: Clinical Physiology of Blood Circulaiton. 2019; 16 (3): 217-227

Quote as: Stankevich Yu.A., Bogomyakova O.B., Vasil'kiv L.M., Tulupov A.A. Features of changes in the hemodynamic characteristics of the main and tissue blood flow in the pathological tortuosity of the internal carotid arteries according to phase-contrast and perfusion magnetic resonance imaging. Сlinical Physiology of Circulation. 2019; 16 (3): 217–27 (in Russ.). DOI: 10.24022/1814-6910-2019-16-3-217-227

Keywords:  hemodynamics internal carotid artery pathological tortuosity morphofunctional features phase-contrast magnetic resonance angiography perfusion perfusion magnetic resonance imaging

Received / Accepted:  18.07.2019/28.08.2019

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Abstract

Objective. To analyze the peculiarities of changes in the main and perfusion blood flow in case of the pathological tortuosity of the internal carotid artery (ICA) using phase-contrast and perfusion MRI.

Material and methods. The study was carried out on the MR-tomograph 1,5 T using a routine protocol, phase contrast and perfusion MR angiography. Focal vascular changes in the brain, indicators of volumetric, linear peak blood flow velocity by the ICA and the values of perfusion characteristics (CBF, CBV, MTT) in its pool were assessed.

Results. The values of the velocity characteristics of the blood flow during the deformation of the ICA, accompanied by the appearance of MR-signs of cerebrovascular insufficiency, were determined; the interrelation of a significant decrease in the blood flow rate and an increase in the severity of dyscirculatory focal brain pathology in the pathology group was revealed. The correlation connections between the values of the bulk velocity of the main blood flow and the regional rate of tissue blood flow were revealed: the frontal lobe of the frontal lobe R = 0.35, the parietal cortex of the parietal lobe R = 0.62, the white matter of the frontal lobe is R = 0.32, the white matter of the parietal lobe is R = 0.33.

Conclusions. Correlations between capillary and main blood flow demonstrate the possibility of using indicators such as blood flow velocity and CBF to assess the main and tissue hemodynamics in assessing the significance of pathological.

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About Authors

  • Yuliya A. Stankevich, Cand. Med. Sc., Junior Researcher; orcid.org/0000-0002-7959-5160
  • Ol’ga B. Bogomyakova, Cand. Med. Sc., Junior Researcher; orcid.org/0000-0002-8880-100X
  • Lyubov’ M. Vasil’kiv, Junior Researcher; orcid.org/0000-0003-1838-8130
  • Andrey A. Tulupov, Dr. Med. Sc. Professor of RAS, Chief Researcher, Head of Laboratory; orcid.org/0000-0002-1277-4113

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