Clinical Physiology of Circulation

Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery


Изменения в функционировании микроциркуляторной системы человека в процессе старения

Link: Clinical Physiology of Blood Circulaiton. 2005; (): -

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Abstract

The ageing features in peripheral blood flow have been studied with laser Doppler flowmetry in healthy volunteers. To reveal the reaction of microvascular bed in response to short-term ischemia the occlusive test has been carried out. To estimate the contribution of rhythmical components in blood flow signal spectral analysis has been used. The age reduction of microcirculation index has been observed at rest. The age increase of pulse-wave amplitude and decrease of respiratory wave amplitude reflecting ageing changes in functioning of arteriolar and venular links of microvascular bed have been shown at rest. In response to short-term ischemia the ageing reduction of borders in functioning of microvascular bed has been revealed.

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