Clinical Physiology of Circulation

Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery


Типы патологического ремоделирования сердца у пациентов с приобретенными пороками митрального клапана

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Link: Clinical Physiology of Blood Circulaiton. 2011; (): -

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Abstract

Analysis and estimation of volume remodelling index (VRI) of heart cavities in patients with acquired mitral valve pathology (MV) is carried out to reveal logics during postoperative heart remodelling associated with intensity of initial pathology. The cohort under study included 316 patients whose structural geometric parameters of heart cavities and their correlation at various periods before and after surgical treatment had been analyzed. Statistically and prognostically significant relationship between VRI and intensity of pathologic remodelling of heart cavities and their ability to recovery in the late periods after surgery (p<0.05) is revealed. As a result three types of pathologic heart remodelling are found depending on the intensity of the initial VRI of heart and prognostic estimation of the late surgical results is carried out. The results obtained give cardiologists authentic criterion to estimate intensity of intracardiac hemodynamic disturbance in patients with mitral valve disease, necessity and rates of radical surgical treatment.

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