Clinical Physiology of Circulation

Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery


Results of mitral valve replacement with mechanical prostheses in elderly patients

Authors: Shchebunyaeva E.A., Muratov R.M., Babenko S.I., Soboleva N.N.

Company:
A.N. Bakoulev Scientific Center for Cardiovascular Surgery of Russian Academy of Medical Sciences, Rublevskoe shosse, 135, Moscow, 121552, Russian Federation

E-mail: Сведения доступны для зарегистрированных пользователей.

Link: Clinical Physiology of Blood Circulaiton. 2014; (): -

Quote as: Shchebunyaeva E.A., Muratov R.M., Babenko S.I., Soboleva N.N. Results of mitral valve replacement with mechanical prostheses in elderly patients. Klinicheskaya Fiziologiya Krovoobrashcheniya. 2014; 2: 32–41.

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Abstract

Objective to study the long-term results of mitral valve replacement with mechanical prostheses in elderly patients.
Material and methods. From 1998 to 2007 Bakoulev SCCS 150 patients underwent mitral valve replacement with mechanical prostheses. Mean age was 63.5±2.6 years. Mean follow-up 7.6±3 years (from 2 months to 13 years).
Results. Actuarial survival after mitral valve replacement with mechanical prostheses at 10 years was 63.7±5.6%, freedom from valve-related mortality was 74.7±5.4%, respectively. There was a trend toward lower mortality in patients with bileaflet mechanical heart valve prostheses.
Actuarial freedom from thromboembolism at 10 years after operation was 69.3±6.1%, freedom from thrombosis – 90.4±3.7%. There was no statistically significant difference in freedom from thromboembolic complications and prosthe- sis thrombosis in patients with tilting disc and bileaflet mechanical heart valve prostheses.
Freedom from bleeding at 10 years was 76.6±5.9%. Freedom from reoperation was 98.7±1.1%.
Conclusion. Mechanical prostheses implanted in mitral position restore adequate hemodynamics, which creates favor- able conditions for the normalization of cardiac function. In elderly patients after mitral valve replacement with mechanical prostheses in the observation period trimmed satisfactory survival. There was high incidence of thromboembolic compli- cations in long-term period, due to poor control of bleeding.

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