Clinical Physiology of Circulation

Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery


Effect of the «3F ENABLE» stent deformation on the hydrodynamic parameters

Authors: Ovcharenko E.A., Klyshnikov K.Yu., Zhuravleva I.Yu.

Company:
Research Institute for Complex Issues of Cardiovascular Diseases, Siberian Branch of the Russian Academy of Medical Sciences, Sosnovyy bul’var, 6, Kemerovo, 650002, Russian Federation

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Link: Clinical Physiology of Blood Circulaiton. 2014; (): -

Quote as: Ovcharenko E.A., Klyshnikov K.Yu., Zhurav- leva I.Yu. Effect of the «3F ENABLE» stent defor- mation on the hydrodynamic parameters. Klinicheskaya Fiziologiya Krovoobrashcheniya. 2014; 2: 41–47.

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Abstract

Objective of the research assessment of the impact the degree of deformation of the prosthesis frame on his hydro- dynamic characteristics in vitro for the purpose of in-depth study of the mechanisms of trans-valvular regurgitation.
Material and methods. Investigation of influence of the radial and elliptical frame deformation on the hydrodynamic parameters was performed in a pulse duplicator using bioprosthesis «3F Enable».
Results. The radial compression of the bioprosthesis demonstrated quadratic dependence of the hydrodynamic perform- ance from the final diameter of the frame. In the case of elliptical frame compression dependence had a linear character.
Actuarial freedom from thromboembolism at 10 years after operation was 69.3±6.1%, freedom from thrombosis – 90.4±3.7%. There was no statistically significant difference in freedom from thromboembolic complications and prosthe- sis thrombosis in patients with tilting disc and bileaflet mechanical heart valve prostheses.
Freedom from bleeding at 10 years was 76.6±5.9%. Freedom from reoperation was 98.7±1.1%.
Conclusion. The study found that compression more than 1 mm and increasing eccentricity e>0,20 of bioprosthesis frame leads to a sharp deterioration of the hydrodynamic characteristics.

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