Clinical Physiology of Circulation

ISSN 1814-6910 (Print)
ISSN 2410-9134 (Online)

 

Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery


Issue's catalogue ➤ КФК. 2018; 15 (3): 149-232 ➤ Острый коронарный синдром при сахарном диабете

Acute coronary syndrome in diabetes mellitus

Authors: M.A. Alekseeva, E.U. Asymbekova

Company:
Bakoulev National Medical Research Center for Cardiovascular Surgery, Ministry of Health of the Russian Federation, Rublevskoe shosse, 135, Moscow, 121552, Russian Federation

E-mail: Сведения доступны для зарегистрированных пользователей.

DOI: https://doi.org/10.24022/1814-6910-2018-15-3-162-168

UDC: 616.132.2-008.6:616.379-008.64

Link: Clinical Physiology of Blood Circulaiton. 2018; 15 (3): 162-168

Quote as: Alekseeva M.A., Asymbekova E.U. Acute coronary syndrome in diabetes mellitus. Clinical Physiology of Circulation. 2018; 15 (3): 162–8 (in Russ.). DOI: 10.24022/1814-6910-2018-15-3-162-168

Keywords:  acute coronary syndrome ischemic heart disease diabetes mellitus

Received / Accepted:  19.03.2018/10.04.2018

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Abstract

The article presents a literary review of epidemiology and the current state of the problem of acute coronary syndrome (ACS) in patients with type 2 diabetes mellitus. In diabetes mellitus, the risk of ischemic heart disease increases by 4 times and causes three-quarters of diabetes-related deaths. The presence of acute coronary syndrome of diabetes mellitus type 2 significantly complicates the course of ACS and worsens the patient's prognosis. The increased risk of mortality observed in patients with diabetes in ACS persists for several years. Adverse forecast in this category of patients is associated with recurrence of myocardial ischemia, left ventricular dysfunction, development of severe heart failure, electrical instability of the myocardium, repeated myocardial infarctions and strokes. Numerous factors of diabetes mellitus contribute to the formation of such a negative prognosis (diffuse lesion of the coronary bed, reduced vasodilatation reserve, decreased fibrinolytic activity of the blood, increased platelet aggregation, autonomic dysfunction, signs of diabetic cardiomyopathy).

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About Authors

  • Alekseeva Mariya Andreevna, Postgraduate; orcid.org/0000-0002-3736-2991
  • Asymbekova El’mira Umetovna, Dr. Med. Sc., Leading Researcher; orcid.org/0000-0002-5422-2069

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