Clinical Physiology of Circulation

Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery


The value of intraoperative autohemoexfusion in transfusion therapy in cardiac surgery patients

Authors: Tsar’kov A.V., Safronova N.N., Andreevskikh A.A., Gladkikh F.A., Gosnits M.V.

Company:
Chelyabinsk Regional Clinical Hospital, Chelyabinsk, Russian Federation

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DOI: https://doi.org/10.24022/1814-6910-2021-18-3-222-230

UDC: 615.38:616.12-089

Link: Clinical Physiology of Blood Circulaiton. 2021; 3 (18): 222-230

Quote as: Tsar’kov A.V., Safronova N.N., Andreevskikh A.A., Gladkikh F.A., Gosnits M.V. The value of intraoperative autohemoexfusion in transfusion therapy in cardiac surgery patients. Clinical Physiology of Circulation. 2021; 18 (3): 222–30 (in Russ.). DOI: 10.24022/1814-6910-2021-18-3-222-230

Received / Accepted:  26.02.2021 / 08.06.2021

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Abstract

Objective. To determine the value of intraoperative autohemoexfusion on transfusion therapy in cardiac surgery patients with the use of cardiopulmonary bypass at the Chelyabinsk Regional Clinical Hospital for the period 2018–2020.

Material and methods. A retrospective analysis of transfusion tactics was carried out in patients (n = 995) who underwent cardiac surgery with cardiopulmonary bypass. The effect of intraoperative autohemoexfusion on the need for transfusion of allogenic blood was assessed, the effect of transfusion of erythrocyte-containing blood components and fresh frozen plasma (FFP) on the duration of mechanical ventilation and the timing of patients' extubation in the postoperative period.

Results. From 2018 to 2020, the number of autologous blood transfusion increased significantly – from 13 to 140, respectively. The volume of transfusion significantly decreased (p < 0.001): 2018 – the volume of blood transfusion 572.8 ± 474.8 ml (95% CI 520.4–625.1 ml), FFP 810.4 ± 388.2 ml (95% CI 767.6–853.2 ml); 2020 – the volume of blood is 287.7 ± 430.1 ml (95% CI 238.4–336.9 ml), FFP 184.4 ± 454.6 ml (95% CI 132.3–236.5 ml). Delayed extubation (> 6 hours) OR 3.5 (95% CI 2.6–4.8) for blood transfusion (V = 0.27) and OR 5.7 (95% CI 4.1–8.0) for FFP transfusion (V = 0.36).

Conclusion. From 2018 to 2020, a decrease in the transfusion of blood and its components was noted in Chelyabinsk regional clinical hospital. The most significant change in tactics was intraoperative autohemoexfusion, which demonstrated sufficient safety and efficacy

About Authors

  • Artem V. Tsar’kov, Anesthesiologist-Intensivist; ORCID
  • Natal’ya N. Safronova, Cand. Med. Sci., Head of Anesthesiology Department No. 1
  • Andrey A. Andreevskikh, Anesthesiologist-Intensivist
  • Filipp A. Gladkikh, Anesthesiologist-Intensivist
  • Maksim V. Gosnits, Anesthesiologist-Intensivist

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