Clinical Physiology of Circulation

Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery


Microcirculation in a critical patient

Authors: Kuligin A.V., Zeulina E.E.

Company:
Razumovsky Saratov State Medical University, Saratov, Russian Federation

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DOI: https://doi.org/10.24022/1814-6910-2022-19-1-82-89

UDC: 612.15:615.099.036.11

Link: Clinical Physiology of Blood Circulaiton. 2022; 1 (19): 82-89

Quote as: Kuligin A.V., Zeulina E.E. Microcirculation in a critical patient. Clinical Physiology of Circulation. 2022; 19 (1): 82–9 (in Russ.). DOI: 10.24022/1814-6910-2022-19-1-82-89

Received / Accepted:  19.11.2021 / 30.11.2021

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Abstract

The cardiovascular system is mastered by students when they receive higher education according to specialty programs based on an anatomical and physiological approach, and the circulatory system at the stage of training highly qualified personnel should be considered from the position of a functional systemic approach. In the functional circulatory system, subsystems are required, which are united by elements that are different in ontogeny. Microcirculation, along with gas exchange, are subsystems of the functional circulatory system. When determining the basis of microcirculation disorders in a critically ill patient, it is necessary to take into account the role of microcirculation in the development of macrocirculation disorders leading to organ dysfunction and failure. Central hemodynamic research methods do not reveal microcirculatory dysfunction and its response to intensive therapy, which can aggravate the violation of perfusion-metabolic relations and lead to dysfunction and organ failure. From this point of view, the cause of microcirculation dysfunction must be sought in the violation of perfusion-metabolic relationships, as a mechanism for the development of a critical state of the patient, the pathognomonic sign of which is a system of multiple acute dysfunctions.

About Authors

  • Aleksandr V. Kuligin, Dr. Med. Sci., Associate Professor, Chief of Chair of Emergency, Anesthesiology Reanimatology Care and Simulation Technologies in Medicine; ORCID
  • Ekaterina E. Zeulina, Cand. Med. Sci., Associate Professor of Chair of Emergency, Anesthesiology Reanimatology Care and Simulation Technologies in Medicine; ORCID

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