Clinical Physiology of Circulation

ISSN 1814-6910 (Print)
ISSN 2410-9134 (Online)

 

Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery


Issue's catalogue ➤ КФК. 2023; 20 (3): 203-320 ➤ Трансторакальная эхо-кардиография с использованием методик тканевой допплерографии и speckle-tracking для оценки биомеханических свойств восходящего отдела аорты. Первый опыт применения в России

Transthoracic echocardiography using tissue Doppler and speckle-tracking techniques to assess biomechanical properties of the ascending aorta. First experience in Russia

Authors: Golukhova E.Z., Pursanova D.M., Mironenko V.A., Mironenko M.Yu., Tkhashokova L.R.

Company:
Bakoulev National Medical Research Center for Cardiovascular Surgery, Moscow, Russian Federation

E-mail: Сведения доступны для зарегистрированных пользователей.

DOI: https://doi.org/10.24022/1814-6910-2023-20-3-278-287

UDC: 616.132.13-073.43

Link: Clinical Physiology of Blood Circulaiton. 2023; 3 (20): 278-287

Quote as: Golukhova E.Z., Pursanova D.M., Mironenko V.A., Mironenko M.Yu., Tkhashokova L.R. Transthoracic echocardiography using tissue Doppler and speckle-tracking techniques to assess biomechanical properties of the ascending aorta. First experience in Russia. Clinical Physiology of Circulation. 2023; 20 (3): 278–87 (in Russ.). DOI: 10.24022/1814-6910-2023-20-3-278-287

Keywords:  aneurysm ascending aorta biomechanics elastic-elastic properties echocardiography tissue Doppler speckle-tracking echocardiography arterial stiffness strain

Received / Accepted:  11.07.2023 / 14.08.2023

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Abstract

Introduction. The currently used parameters for predicting the development of fatal complications of AAA (ascending aortic aneurysms) – absolute diameter of the ascending aorta (AA) and its growth rate – do not have sufficient reliability required for accurate stratification of patients by risk of disease progression. In this regard the assessment of biomechanical properties of AA is promising. Purpose of the study: comparative analysis of AA wall biomechanical properties in patients with AAA and in the control group using transthoracic ultrasound techniques – tissue Doppler (TD) and speckle-tracking echocardiography (STE).

Material and methods. 40 patients (27 men, 13 women) in two main groups were included in the study: with AAA with diameter more than 45 mm (n = 20) and control group with AA diameter less than 40 mm (n = 20). Transthoracic echocardiography was performed according to the standard technique, as well as using TD and STE (adapted programs used for myocardial assessment).

Results. Mean values of AA diameter in the groups were significantly different and were of 54 [46; 58] mm vs. 30 [29; 34] mm, respectively (p<0.05). In AAA patients, compares to the control group, significant differences in aortic wall characteristics were revealed – decreased deformation and distensibility, as well as increased elasticity and stiffness (p<0.05). The analysis of TD results showed that the maximum and minimum AA diameters, as well as the velocity index S (systolic displacement velocity) were significantly different between the groups with AA and the control group (p<0.05). The analysis of STE results showed that in the group with AAA the index of longitudinal deformation was significantly lower in two segments (out of four analyzed) – anterior sinus and posterior AA (p<0.05). Other indices – A and E index at TD – as well as longitudinal deformation of the other two segments at STE (anterior AA and posterior sinus) were not statistically significantly different (p>0.05).

Conclusion. Initial results has shown that the use of TD and STE ultrasound techniques allows non-invasive assessment of biomechanical properties of dilated AA wall. It was found that in AAA, compared to the control group, statistically significantly decreased TD indicators – minimum and maximum AA diameters, systolic displacement velocity, as well as STE indicators – longitudinal deformation of the anterior sinus and posterior AA (p < 0.05).

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About Authors

  • Elena Z. Golukhova, Dr. Med. Sci., Professor, Academician of RAS, Director of the Center; ORCID
  • Diana M. Pursanova, Dr. Med. Sci., Professor of the Chair of Radiology, Senior Researcher; ORCID
  • Vladimir A. Mironenko, Dr. Med. Sci., Head of the Department of Reconstructive Surgery and Aortic Arch, Cardiovascular Surgeon; ORCID
  • Marina Yu. Mironenko, Cand. Med. Sci., Head of the Department of Ultrasonic Diagnostics, Ultrasonic Diagnostician; ORCID
  • Luiza R. Tkhashokova, Postgraduate; ORCID

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