Clinical Physiology of Circulation

Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery


Изменения параметров легочной гемодинамики, геометрии и функции правых и левых отделов сердца у больных хронической обструктивной болезнью легких в процессе динамического наблюдения

Link: Clinical Physiology of Blood Circulaiton. 2007; (): -

Full text:  

Abstract

Obtained data of changes in parameters of pulmonary hemodynamics, geometry, left and right heart function in patients with chronic obstructive pulmonary disease showed the progressive increase of pulmonary hypertension. We noted parallel increase of pulmonary hypertension and hypertrophy, dilatation of right ventricle, dilatation of right and left atrium, hypertrophy of left ventricle. We revealed the influence of initial expressiveness for bronchial obstructive syndrome, respiratory insufficiency, hypoxemia on the level of systolic pulmonary pressure, expressiveness of right ventricle hypertrophy and dilatation, right ventricular diastolic function through 12 and 24 months. During the first year of observation we noted parallel comparable increase of pulmonary hypertension, right ventricle hypertrophy and dilatation. But if during the next year of observation the rates of pulmonary hypertension and right ventricle hypertrophy reduce, dilatation of right ventricle continues. During a 2-year observation we noticed progressive remodelling of the left heart: increase of end-diastolic size in left atrium and ventricle, increase of thickness of left ventricle posterior wall and interventricular septum, left ventricle myocardial mass index.

References

1. Васюк Ю. А. Возможности и ограничения эхокардиографического исследования в оценке ремоделирования левого желудочка при ХСН // Сердечная недостаточность. - 2003. - № 2. - С. 107-110.
2. Сильвестров В. П., Суровов Ю. А., Семин С. Н. Актуальные вопросы диагностики, профилактики и лечения хронического легочного сердца // Тер. арх. - 1985. - № 11. - С. 104-109.
3. Стандарты по диагностике и лечению больных хронической обструктивной болезнью легких (ATS/ERS, 2004). Пер. с англ. / Под ред. А. Г. Чучалина. - М.: Атмосфера, 2005. - 96 с.
4. Федорова Т. А. Хроническое легочное сердце // Хронические обструктивные болезни легких. - М.: БИНОМ - СПб.: Невский Диалект, 1998. - С. 192-216.
5. Chemla D., Castelain V., Herve P. et al. Haemodynamic evaluation of pulmonary hypertension // Eur. Respir. J. - 2002. - Vol. 20. - P. 1314-1331.
6. Higham M. A., Dawson D., Joshi J. et al. Utility of echocardiography in assessment of pulmonary hypertension secondary to COPD // Ibid. - 2001. - Vol. 17. - P. 350-355.
7. MacNee W. Pathophisiology of cor pulmonale in chronic obstructive pulmonary disease // Amer. J. Respir. Crit. Care. Med. - 1994. - Vol. 150. - P. 833-852.
8. McQuillan B. M., Picard M. H., Leavitt M. et al. Clinical Correlates and reference intervals for pulmonary artery systolic pressure among echocardiographically normal subjects // Circulations. - 2001. - Vol. 104. - P. 2797-2802.
9. Oswald-Mammosser M., Weitzenblum E., Quoix E. et al. Prognostic factors in COPD patients receiving long-term oxygen therapy // Chest. - 1995. - Vol. 107. - P. 1193-1198.
10. Weitzenblum E. Chronic cor pulmonale // Heart. - 2003. - Vol. 89, № 2. - P. 225-230.
11. Weitzenblum E., Hirth C., Ducolone A. et al. Prognosis value of pulmonary artery pressure in chronic obstructive pulmonary disease // Thorax. - 1981. - Vol. 36. - P. 752-758.
12. Weitzenblum E., Loiseau A., Hirth C. et al. Course of pulmonary haemodynamics in patients with chronic obstructive pulmonary disease // Chest. - 1979. - Vol. 75. - P. 656-662.

 If you found mistakes, select text and press Alt+A