Clinical Physiology of Circulation

Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery


Functional capacity of endothelium and processes of cardiovascularremodeling in patients with arterial hypertension

Authors: Grygorycheva E. A., Volkova E. G.

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Link: Clinical Physiology of Blood Circulaiton. 2008; (): -

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Abstract

320 patients with an arterial hypertension of I-II degrees, at the age of 40-59 years are surveyed. Assay with a reactive hyperemia of a humeral artery, ultrasonic doppler imaging middle cerebrate arteries and actuate arteries of kidneys was spent, definition of a hypertrophy of a left ventricle, type a left ventricle remodeling, measurement of a thickness of an intima-media in the common carotid artery were performed. At patients with the broken ability of a humeral artery to a relaxation the complex of changes testifying to general dysfunction of heart (concentric type of left ventricle remodeling) and a vascular bed (blood flow depression in middle cerebrate artery and a parenchymatous renal blood flow) is taped. These facts allow to offer ultrasonic indicators of function of an endothelium as markers of general vascular dysfunction.

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