Clinical Physiology of Circulation

Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery


Гематологические и биохимические предикторы течения послеоперационного периода у кардиохирургических больных (ретроспективное исследование)

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Link: Clinical Physiology of Blood Circulaiton. 2012; (): -

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Abstract

Objective. The aim of the study was to determine the significance of certain laboratory values (and time of blood sampling for evaluation of these rates) in prediction of mortality in cardiosurgical patients who had undergone cardiac surgery under cardiopulmonary bypass (CPB). Material and methods. The retrospective study included 189 adult patients who underwent cardiac surgeries under CPB in 2011. Results. Multivariate analysis showed that hematocrit value of less than 28% at the end of surgery, urinary level on the third day of more than 15 mmol/l, lymphocyte count on the third and fifth days of less than 10% were clinically and statistically significant predictors of mortality. Increased lactate level of more than 3.0 mmol/l and 10 mmol/l at the end and in 5 hours after surgery, respectively, was associated with significant mortality risk, but this value cant provide satisfactory quality of unfavorable outcome prediction and its significance should be considered individually for each patient. Conclusion. Increased lactate level as a predictor of inadequate tissue perfusion since only lactate level cant provide the assessment of disease severity and prognosis.

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