Научно-практический журнал
«Клиническая физиология кровообращения»

ISSN 1814-6910 (Print)
ISSN 2410-9134 (Online)

 

Главный редактор

Лео Антонович Бокерия, доктор медицинских наук, профессор, академик РАН и РАМН, президент ФГБУ «НМИЦ ССХ им. А.Н. Бакулева» МЗ РФ


Каталог статей ➤ КФК. 2025; 22 (1): 1-114 ➤ Коморбидные состояния при ишемической болезни сердца: патогенетические взаимосвязи, клинические риски и последствия

Коморбидные состояния при ишемической болезни сердца: патогенетические взаимосвязи, клинические риски и последствия

Авторы: Мамалыга М.Л.

Организация:
ФГБУ «Национальный медицинский исследовательский центр сердечно-сосудистой хирургии им. А.Н. Бакулева» Минздрава России, Москва, Российская Федерация

Для корреспонденции: Сведения доступны для зарегистрированных пользователей.

Раздел: Обзоры

DOI: https://doi.org/10.24022/1814-6910-2025-22-1-5-20

УДК: 616.12-008.46

Библиографическая ссылка: Клиническая физиология кровообращения. 2025; 22 (1): 5-20

Цитировать как: Мамалыга М.Л. . Коморбидные состояния при ишемической болезни сердца: патогенетические взаимосвязи, клинические риски и последствия. Клиническая физиология кровообращения. 2025; 22 (1): 5-20. DOI: 10.24022/1814-6910-2025-22-1-5-20

Ключевые слова: коморбидность, ишемическая болезнь сердца, патогенетические механизмы, сахарный диабет, хроническая болезнь почек, хроническая обструктивная болезнь легких, гипотиреоз, синдром обструктивного апноэ сна, депрессия

Поступила / Принята к печати:  21.01.2025 / 31.01.2025

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Аннотация

В обзоре представлен детальный анализ результатов клинических исследований, посвященных изучению патогенетических механизмов, лежащих в основе взаимосвязи между ишемической болезнью сердца (ИБС) и коморбидными ей состояниями, которые в настоящее время остаются во многом малоизученными. Публикация направлена на информирование практикующих врачей об особенностях проявления коморбидных нарушений при ИБС, а также о провоцирующих их механизмах. Несмотря на очевидную актуальность проблемы, многие аспекты взаимосвязи ИБС и сопутствующих заболеваний требуют дальнейшего фундаментального изучения, необходимого для разработки и внедрения инновационных методов диагностики и лечения. При планировании стратегии лечения пациентов с ИБС и назначении кардиотерапии важно учитывать, что наиболее высокому риску развития коморбидных заболеваний подвержены пожилые пациенты, у которых с возрастом увеличивается предрасположенность к сердечно-сосудистым заболеваниям, усугубляющаяся наличием сопутствующих патологий. Системный анализ исследований направлен на формирование целостного понимания патологических механизмов, лежащих в основе взаимосвязи ИБС и коморбидных ей состояний. Результаты исследования призваны способствовать разработке новых стратегий своевременной диагностики, профилактики и персонализированного лечения таких пациентов. Это особенно важно для оптимизации клинических результатов и повышения качества жизни пациентов, страдающих сложными формами сердечно-сосудистых патологий.

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  6. Mamalyga M.L. Contemporary problems of cardiovascular disorders at diabetes mellitus. Int. J. Diabetes Endocrinol. 2016; 1 (1): 1–7. DOI: 10.11648/j.ijde.20160101.11
  7. Guzik T.J., Touyz R.M. Oxidative stress, inflammation, and vascular aging in hypertension. Hypertension. 2017; 70 (4): 660–667. DOI: 10.1161/HYPERTENSIONAHA.117.07802
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Об авторах

Мамалыга Максим Леонидович, д-р мед. наук, вед. науч. сотрудник; ORCID

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