Clinical Physiology of Circulation

Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery


Comorbid conditions in ischemic heart disease: pathogenetic interconnections, clinical risks, and consequences K

Authors: Mamalyga M.L.

Company:
Bakoulev National Medical Research Center for Cardiovascular Surgery, Moscow, Russian Federation

E-mail: Сведения доступны для зарегистрированных пользователей.

DOI: https://doi.org/10.24022/1814-6910-2025-22-1-5-20

UDC: 616.12-008.46

Link: Clinical Physiology of Blood Circulaiton. 2025; 22 (1): 5-20

Quote as: Mamalyga M.L. Comorbid conditions in ischemic heart disease: pathogenetic interconnections, clinical risks, and consequences. Clinical Physiology of Circulation. 2025; 22 (1): 5–20 (in Russ.). DOI: 10.24022/1814-6910-2025-22-1-5-20

Received / Accepted:  21.01.2025 / 31.01.2025

Download
Full text:  

Abstract

The review presents a detailed analysis of the results of clinical studies devoted to the study of the pathogenetic mechanisms underlying the relationship between congenital heart disease (CHD) and comorbid conditions, which currently remain largely poorly understood. The publication is aimed at informing practitioners about the features of the manifestation of comorbid disorders in CHD, as well as about the mechanisms of development that provoke them. The relevance of the problem is obvious, but many aspects of the relationship between CHD and comorbid conditions require further fundamental study, which is necessary for the development and implementation of innovative methods of diagnosis and treatment of diseases. When planning a strategy for the treatment of CHD and prescribing cardiotherapy, it is important to take into account that elderly patients are most at risk of developing comorbid diseases, in which the predisposition to cardiovascular diseases increases with age, which is aggravated by the presence of concomitant pathologies. Systematic analysis of research is aimed at developing a holistic understanding of the pathological mechanisms underlying the relationship between CHD and comorbid conditions. The results of the study are intended to contribute to the development of new strategies for timely diagnosis, prevention and personalized treatment of such patients. This is especially important for optimizing clinical outcomes and improving the quality of life of patients suffering from complex forms of cardiovascular diseases.

References

ersdfh rdtfjtyd f jtdyu j5tdyjjtdyj

About Authors

Maksim L. Mamalyga, Dr. Med. Sci., Leading Researcher; ORCID

 If you found mistakes, select text and press Alt+A