Clinical Physiology of Circulation

Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery


Features of the clinical course of the early postoperative period in patients with a history of COVID-19 after correction of valvular heart pathology with cariopulmonary bypass

Authors: Rybka M.M., Goncharov A.A., Yudin G.V., Dibin D.A., Nurkaev M.T.

Company:
Bakoulev National Medical Research Center for Cardiovascular Surgery, Moscow, Russian Federation

E-mail: Сведения доступны для зарегистрированных пользователей.

DOI: https://doi.org/10.24022/1814-6910- 2024-21-1-36-44

UDC: [616.126.3-089-06]+578.834.11

Link: Clinical Physiology of Blood Circulaiton. 2024; 21 (1): 36-44

Quote as: Rybka M.M., Goncharov A.A., Yudin G.V., Dibin D.A., Nurkaev M.T. Features of the clinical course of the early postoperative period in patients with a history of COVID-19 after correction of valvular heart pathology with cariopulmonary bypass. Clinical Physiology of Circulation. 2024; 21 (1): 36–44 (in Russ.). DOI: 10.24022/1814-6910- 2024-21-1-36-44

Received / Accepted:  18.01.2024 / 05.03.2024

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Abstract

The aim – to analyze the clinical course of the early postoperative period and the structure of organ dysfunction in patients undergoing surgery correction of valvular heart disease who underwent COVID-19.

Material and methods. The study is retrospective, cohort, and single-center. From a pool of 1204 patients, 811 were selected for the study, operated at the Bakoulev National Medical Research Center for Cardiovascular Surgery in the period from 2021–2022 (COVID – 237 patients, non-COVID – 574 patients). The clinical course of the early postoperative period was analyzed (duration of respiratory support, duration of stay in the intensive care unit, hospital mortality, state of left ventricle myocardial contractility). The frequency of development and structure of organ dysfunction were also studied.

Results. In patients of the COVID group, acute respiratory failure was significantly more common 13.1% versus 5.8% in the non-COVID group (odds ratio (OR) 2.47; 95% confidencial interval (CI) 1.47–4.13; p = 0.001). The need for a tracheostomy was higher in the COVID group: 3.4% versus 0.5% in the non-COVID group (OR 6.65; 95% CI 1.75– 25.29; p = 0.003). COVID group patients were more likely to develop acute respiratory distress syndrome: 2.1% versus 0.4% in the non-COVID group (p = 0.025). Pneumonia was significantly more common in the COVID group of 6.3% versus 3.0% in the non-COVID group (p = 0.03).

Conclusion. Nine months after the COVID-19 infection, the number of respiratory complications was significantly higher in patients with valvular apparatus pathology after artificial circulation surgery. Other postoperative complications are also more common in the COVID-19 group; however, they do not achieve a statistically significant difference. Cardiac surgery can be performed safely 9 months after the COVID-19 infection, but special caution should be observed with respect to this group of patients.


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About Authors

  • Mikhail M. Rybka, Dr. Med. Sci., Deputy Director of Anesthesiology and Intensive Care, Head of the Department; ORCID
  • Andrey A. Goncharov, Cand. Med. Sci., Anesthesiologist-Resuscitator; ORCID
  • Gennadiy V. Yudin, Dr. Med. Sci., Head of Department; ORCID
  • Denis A. Dibin, Anesthesiologist-Resuscitator; ORCID
  • Marufjon T. Nurkaev, Postgraduate; ORCID

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