Clinical Physiology of Circulation

Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery


Right ventricular remodeling in patients after aortocoronary bypass surgery

Authors: Dmitriev O.V.1, Terеshina O.V.2, Gryaznova D.A.1, Luchkina E.A, 1 Poltaeva M.N.1, Generalova A.V.1, Vachev A.N.1

Company:
1 Samara State Medical University, Ministry of Health of Russia, Samara, Russian Federation
2 Royal Brompton Hospital, London, UK

E-mail: Сведения доступны для зарегистрированных пользователей.

DOI: https://doi.org/10.24022/1814-6910-2024-21-2-107-116

UDC: 616.124.3-089.86

Link: Clinical Physiology of Blood Circulaiton. 2024; 21 (2): 107-116

Quote as: Dmitriev O.V., Tereshina O.V., Gryaznova D.A., Luchkina E.A., Poltaeva M.N., Generalova A.V., Vachev A.N. Remodeling of the right ventricle in patients after ACS surgery. Clinical Physiology of Circulation. 2024; 21 (2): 107–116 (in Russ.). DOI: 10.24022/1814-6910-2024-21-2-107-116

Received / Accepted:  27.05.2024 / 21.06.2024

Download
Full text:  

Abstract

Objective: to determine the significance of echocardiographic criteria to assess reverse remodeling of the right ventricular (RV) after coronary artery bypass grafting (CABG) surgery in patients with baseline right ventricular myocardial infarction (RVMI).

Material and methods. The study retrospectively analyzed 104 treated patients with tricuspid coronary lesions in 2022. Depending on the initial right RVMI anamnesis, the patients were divided into 2 groups: the first group (n = 97) – patients without RVMI, the second group (n = 7) – patients with RVMI anamnesis. All patients underwent CABG surgery. Basal diameter (mm), mean diameter (mm), diameter of the proximal part of the outflow tract (mm), diameter of the distal part of the outflow tract (mm), TAPSE (mm) were evaluated by echo before and after the operation.

Results. All patients in group I after CABG surgery had clinical improvement in the form of disappearance of clinical signs of angina pectoris and improvement of RV function according to cardiac echo data. In group II 2 patients died due to the development of RVMI. All survivors patients after CABG operation had disappearance of clinical manifestations of angina pectoris, 2 patients still had dyspnea. Group II patients showed more pronounced remodeling and improvement of RV function according to echo data.

Conclusion. CABG surgery leads to clinical improvement and significantly affects the structure of the right ventricle in patients with initial ventricular dysfunction. Echo parameters such as mean right ventricular diameter, proximal outflow tract diameter, and TAPSE change most significantly.

References

  1. Abdeltawab A.A., Elmahmoudy A.M., Elnammas W., Mazen A. Assessment of right ventricular function after successful revascularization for acute anterior myocardial infarction without right ventricular infarction by echocardiography. J. Saudi Heart Assoc. 2019; 31 (4): 261–268. DOI: 10.1016/j.jsha.2019.07.001
  2. Sanders A.O. Coronary thrombosis with complete heart-block and relative ventricular tachycardia a case report. Am. Heart J. 1931; 6: 820–823. DOI: 10.1016/s0002-8703(31)90367-0
  3. Cohn J.N., Guiha N.H., Broder M.I., Limas C.J. Right ventricular infarction: clinical and hemodynamic features. Am. J. Cardiol. 1974; 33: 209–214. DOI: 10.1016/0002-9149(74)90276-8
  4. Kumar R., Kumar P., Srivastava P.K., Kumar P. Echocardiographic and angiographic assessment of right ventricular function and right coronary artery stenosis in acute inferior wall myocardial infarction. Cureus. 2023; 15 (10): е46403. DOI: 10.7759/cureus.46403
  5. Femia G., French J.K., Juergens C., Leung D., Lo S. Right ventricular myocardial infarction: pathophysiology, clinical implications and management. Rev. Cardiovasc Med. 2021; 22 (4): 1229–1240. DOI: 10.31083/j.rcm2204131
  6. Nägele M.P., Flammer A.J. Heart failure after right ventricular myocardial infarction. Curr. Heart Fail. Rep. 2022; 19 (6): 375–385. DOI: 10.1007/s11897-022-00577-8
  7. Kanwar M.K., Everett K.D., Gulati G., Brener M.I., Kapur N.K. Epidemiology and management of right ventricular-predominant heart failure and shock in the cardiac intensive care unit. Eur. Heart J. Acute Cardiovasc. Care. 2022; 11 (7): 584–594. DOI: 10.1093/ehjacc/ zuac063
  8. Трисветова Е.Л., Зыбалова Т.С., Пономаренко И.Н. Хроническая правожелудочковая сердечная недостаточность: причины, диагностика, лечение. Медицинские новости. 2017; 1: 31–36.
  9. Baghel P.K., Tripathi S.K., Vahab A.A., Aggarwal P. Assessment of right ventricular function in patients with acute myocardial infarction. Cureus. 2022; 14 (2): e22399. DOI: 10.7759/cureus.22399
  10. Wu J., Huang X., Huang K., Gao Q., Chen X., Tian Y. et al. The non-invasive echocardiographic assessment of right ventricular myocardial work in a healthy population. Acta Cardiol. 2023; 78 (4): 423–432. DOI: 10.1080/00015385.2023.2189870
  11. Islamova M.R., Lazarev P.V., Safarova A.F., Kobalava Zh.D. The value of right ventricular dysfunction and right ventricular-pulmonary artery coupling in chronic heart failure: the role of echocardiography. Kardiologiia. 2018; 58 (5): 82–90. DOI: 10.18087/cardio.2018.5.10124
  12. Голухова Е.З., Асланиди И.П., Сокольская Н.О., Пурсанова Д.М., Копылова Н.С., Хачатрян А.Г. Комплексная ультразвуковая оценка гемодинамических параметров сердца и почек в ранней диагностике осложнений после аортокоронарного шунтирования. Клиническая физиология кровообращения. 2023; 20 (1): 56–66. DOI: 10.24022/1814-6910-2023-20-1-56-66
  13. Сокольская Н.О., Копылова Н.С., Иванов А.В., Кокшенев И.В. Анатомия и функция правого желудочка. Этиология, патогенез и современные аспекты эхокардиографической оценки правожелудочковой недостаточности. Клиническая физиология кровообращения. 2020; 17 (4): 266–283. DOI: 10.24022/1814-6910-2020-17-4-266-283
  14. Vandenheuvel M., Bouchez S., Wouters P., Mauermann E. Assessing right ventricular function in the perioperative setting, part i: echo-based measurements. Anesthesiol. Clin. 2019; 37 (4): 675–695. DOI: 10.1016/j.anclin.2019.08.011
  15. Novo G., Almeida A.G., Nobile D., Morreale P., Fattouch K., Di Lisi D. et al. Right ventricle function in patients with anterior myocardial infarction: are we sure it is not involved? Curr. Probl. Cardiol. 2022; 47 (9): 101277. DOI: 10.1016/j.cpcardiol.2022.101277
  16. Rallidis L.S., Makavos G., Nihoyannopoulos P. Right ventricular involvement in coronary artery disease: role of echocardiography for diagnosis and prognosis. J. Am. Soc. Echocardiogr. 2014; 27 (3): 223–229. DOI: 10.1016/j.echo.2013.12.001
  17. Rudski L.G., Lai W.W., Afilalo J., Hua L., Handschumacher M.D., Chandrasekaran K. et al. Guidelines for the echocardiographic assessment of the right heart in adults: a report from the American Society of Echocardiography. Endorsed by the European Association of Echocardiography, a registered branch of the European Society of Cardiology. J. Am. Soc. Echocardiogr. 2010; 23 (7): 685–713. DOI: 10.1016/j.echo.2010.05.010
  18. Moceri P., Duchateau N., Baudouy D., Schouver E.-D., Leroy S., Squara F. et al. Three-dimensional right-ventricular regional deformation and survival in pulmonary hypertension. Eur. Heart J. Cardiovasc. Imaging. 2018; 19 (4): 450–458. DOI:10.1093/ehjci/jex163
  19. Geyer H., Caracciolo G., Abe H. Assessment of myocardial mechanics using speckle tracking echocardiography: fundamentals and clinical applications. J. Am. Soc. Echocardiogr. 2010; 23 (4): 351–369. DOI:10.1016/j.echo.2010.02.015
  20. Бабенко С.И., Титов Д.А., Мироненко М.Ю., Донцова В.И., Казумян Б.В. Систолическая функция правого желудочка при тяжелой функциональной недостаточности трикуспидального клапана: прогностическая значимость продольной деформации. Креативная кардиология. 2023; 17 (3): 341–349. DOI: 10.24022/1997-3187-2023-17-3-341-349
  21. Голухова Е.З., Сливнева И.В., Мамалыга М.Л., Марапов Д.И., Алехин М.Н., Скопин И.И., Антонова Д.Е. Продольная деформация свободной стенки правого желудочка по данным спекл-трекинг эхокардиографии как прогностический критерий неблагоприятных исходов. Российский кардиологический журнал. 2021; 26 (4): 4417. DOI: 10.15829/1560-4071-20214417
  22. Голухова Е.З., Сливнева И.В., Скопин И.И., Фарулова И.Ю., Пирушкина Ю.Д., Мурысова Д.В. и др. Правожелудочковая дисфункция в качестве предиктора осложнений в кардиохирургии левых пороков сердца. Российский кардиологический журнал. 2023; 28 (6): 5264. DOI: 10.15829/1560-4071-2023-5264
  23. Zaidi A., Knight D.S., Augustine D.X., Harkness A., Oxborough D., Pearce K. et al.; Education Committee of the British Society of Echocardiography. Echocardiographic assessment of the right heart in adults: a practical guideline from the British Society of Echocardiography. Echo. Res. Pract. 2020; 7 (1): G19–G41. DOI: 10.1530/ERP-19-0051
  24. Park J.H., Park M.M., Farha S., Sharp J., Lundgrin E., Comhair S. et al. Impaired global right ventricular longitudinal strain predicts long- term adverse outcomes inpatients with pulmonary arterial hypertension. J. Cardiovasc. Ultrasound. 2015; 23 (2): 91–99. DOI: 10.4250/ jcu.2015.23.2.91
  25. Кулагина Т.Ю., Сандриков В.А., Ван Е.Ю., Зябирова Р.З., Петрова Ю.Н. Оценка функции правого и левого желудочков и взаимодействия между ними у пациентов с ишемической болезнью сердца, осложненной митральной недостаточностью. Кардиология. 2022; 62 (1): 46–56. DOI: 10.18087/cardio.2022.1.n1695
  26. Архипов О.Г., Сумин А.Н. Диастолическая дисфункция правого желудочка у больных ишемической болезнью сердца. Российский кардиологический журнал. 2017; 3: 37–45. DOI: 10.15829/1560-4071-2017-3-37-45
  27. Alam M., Wardell J., Andersson E., Samad B.A., Nordlander R. Right ventricular function in patients with first inferior myocardial infarction: assessment by tricuspid annular motion and tricuspid annular velocity. Am. Heart J. 2000; 139 (4): 710–715. DOI: 10.1016/ s00028703(00)90053-x
****
  1. Abdeltawab A.A., Elmahmoudy A.M., Elnammas W., Mazen A. Assessment of right ventricular function after successful revascularization for acute anterior myocardial infarction without right ventricular infarction by echocardiography. J. Saudi Heart Assoc. 2019; 31 (4): 261–268. DOI: 10.1016/j.jsha.2019.07.001
  2. Sanders A.O. Coronary thrombosis with complete heart-block and relative ventricular tachycardia a case report. Am. Heart J. 1931; 6: 820–823. DOI: 10.1016/s0002-8703(31)90367-0
  3. Cohn J.N., Guiha N.H., Broder M.I., Limas C.J. Right ventricular infarction: clinical and hemodynamic features. Am. J. Cardiol. 1974; 33: 209–214. DOI: 10.1016/0002-9149(74)90276-8
  4. Kumar R., Kumar P., Srivastava P.K., Kumar P. Echocardiographic and angiographic assessment of right ventricular function and right coronary artery stenosis in acute inferior wall myocardial infarction. Cureus. 2023; 15 (10): е46403. DOI: 10.7759/cureus.46403
  5. Femia G., French J.K., Juergens C., Leung D., Lo S. Right ventricular myocardial infarction: pathophysiology, clinical implications and management. Rev. Cardiovasc Med. 2021; 22 (4): 1229–1240. DOI: 10.31083/j.rcm2204131
  6. Nägele M.P., Flammer A.J. Heart failure after right ventricular myocardial infarction. Curr. Heart Fail. Rep. 2022; 19 (6): 375–385. DOI: 10.1007/s11897-022-00577-8
  7. Kanwar M.K., Everett K.D., Gulati G., Brener M.I., Kapur N.K. Epidemiology and management of right ventricular-predominant heart failure and shock in the cardiac intensive care unit. Eur. Heart J. Acute Cardiovasc. Care. 2022; 11 (7): 584–594. DOI: 10.1093/ehjacc/ zuac063
  8. Trisvetova E.L., Zybalova T.S., Ponomarenko I.N. Chronic right ventricular heart failure: causes, diagnosis, treatment. Medicinskie Novosti (Medical News). 2017; 1: 31–36 (in Russ.).
  9. Baghel P.K., Tripathi S.K., Vahab A.A., Aggarwal P. Assessment of right ventricular function in patients with acute myocardial infarction. Cureus. 2022; 14 (2): e22399. DOI: 10.7759/cureus.22399
  10. Wu J., Huang X., Huang K., Gao Q., Chen X., Tian Y. et al. The non-invasive echocardiographic assessment of right ventricular myocardial work in a healthy population. Acta Cardiol. 2023; 78 (4): 423–432. DOI: 10.1080/00015385.2023.2189870
  11. Islamova M.R., Lazarev P.V., Safarova A.F., Kobalava Zh.D. The value of right ventricular dysfunction and right ventricular-pulmonary artery coupling in chronic heart failure: the role of echocardiography. Kardiologiia. 2018; 58 (5): 82–90. DOI: 10.18087/cardio.2018.5.10124
  12. Golukhova E.Z., Aslanidis I.P., Sokolskaya N.O., Pursanova D.M., Kopylova N.S., Khachatryan A.G. Comprehensive ultrasound for heart and kidney hemodynamic assessment in the early diagnosis of complications after coronary artery bypass grafting surgery. Clinical Physiology of Circulation. 2023; 20 (1): 56–66 (in Russ.). DOI: 10.24022/1814-6910-2023-20-1-56-66
  13. Sokol’skaya N.O., Kopylova N.S., Ivanov A.V., Kokshenev I.V. Anatomy and function of the right ventricle. Etiology, pathogenesis and modern aspects of echocardiographic evaluation of right ventricular failure. Clinical Physiology of Circulation. 2020; 17 (4): 266–283 (in Russ.). DOI: 10.24022/1814-6910-2020-17-4-266-283
  14. li>Vandenheuvel M., Bouchez S., Wouters P., Mauermann E. Assessing right ventricular function in the perioperative setting, part i: echo-based measurements. Anesthesiol. Clin. 2019; 37 (4): 675–695. DOI: 10.1016/j.anclin.2019.08.011
  15. Novo G., Almeida A.G., Nobile D., Morreale P., Fattouch K., Di Lisi D. et al. Right ventricle function in patients with anterior myocardial infarction: are we sure it is not involved? Curr. Probl. Cardiol. 2022; 47 (9): 101277. DOI: 10.1016/j.cpcardiol.2022.101277
  16. Rallidis L.S., Makavos G., Nihoyannopoulos P. Right ventricular involvement in coronary artery disease: role of echocardiography for diagnosis and prognosis. J. Am. Soc. Echocardiogr. 2014; 27 (3): 223–229. DOI: 10.1016/j.echo.2013.12.001
  17. Rudski L.G., Lai W.W., Afilalo J., Hua L., Handschumacher M.D., Chandrasekaran K. et al. Guidelines for the echocardiographic assessment of the right heart in adults: a report from the American Society of Echocardiography. Endorsed by the European Association of Echocardiography, a registered branch of the European Society of Cardiology. J. Am. Soc. Echocardiogr. 2010; 23 (7): 685–713. DOI: 10.1016/j.echo.2010.05.010
  18. Moceri P., Duchateau N., Baudouy D., Schouver E.-D., Leroy S., Squara F. et al. Three-dimensional right-ventricular regional deformation and survival in pulmonary hypertension. Eur. Heart J. Cardiovasc. Imaging. 2018; 19 (4): 450–458. DOI:10.1093/ehjci/jex163
  19. Geyer H., Caracciolo G., Abe H. Assessment of myocardial mechanics using speckle tracking echocardiography: fundamentals and clinical applications. J. Am. Soc. Echocardiogr. 2010; 23 (4): 351–369. DOI:10.1016/j.echo.2010.02.015
  20. Babenko S.I., Titov D.A., Mironenko M.Yu., Dontsova V.I., Kazumyan B.V. Right ventricular systolic function in severe functional tricuspid regurgitation: predictive value of longitudinal strain. Creative Cardiology. 2023; 17 (3): 341–349 (in Russ.). DOI: 10.24022/1997-3187-2023-17-3-341-349
  21. Golukhova E.Z., Slivneva I.V., Mamalyga M. L., Marapov D.I., Alekhin M.N., Skopin I.I., Antonova D.E. Right ventricular free-wall longitudinal speckle tracking strain as a prognostic criterion of adverse outcomes in patients with pulmonary hypertension: a systematic review and meta-analysis. Russian Journal of Cardiology. 2021; 26 (4): 4417 (in Russ.). DOI: 10.15829/1560-4071-20214417
  22. Golukhova E.Z., Slivneva I.V., Skopin I.I., Farulova I.Y., Pirushkina Yu.D., Murysova D.V., Marapov D.I., Volkovskaya I.V. Right ventricular dysfunction as a pre dictor of complicated course in left heart surgery. Russian Journal of Cardiology. 2023; 28 (6): 5264 (in Russ.). DOI: 10.15829/1560-4071-2023-5264
  23. Zaidi A., Knight D.S., Augustine D.X., Harkness A., Oxborough D., Pearce K. et al.; Education Committee of the British Society of Echocardiography. Echocardiographic assessment of the right heart in adults: a practical guideline from the British Society of Echocardiography. Echo. Res. Pract. 2020; 7 (1): G19–G41. DOI: 10.1530/ERP-19-0051
  24. Park J.H., Park M.M., Farha S., Sharp J., Lundgrin E., Comhair S. et al. Impaired global right ventricular longitudinal strain predicts long- term adverse outcomes in patients with pulmonary arterial hypertension. J. Cardiovasc. Ultrasound. 2015; 23 (2): 91–99. DOI: 10.4250/ jcu.2015.23.2.91
  25. Kulagina T.Yu., Sandrikov V.A., Van E.Yu., Zyabirova R.Z., Petrova Yu.N. Evaluation of right and left ventricular function in patients with ischemic heart disease complicated by mitral insufficiency. Kardiologiia. 2022; 62 (1): 46–56 (in Russ.). DOI: 10.18087/cardio.2022.1.n1695
  26. Arkhipov O.G., Sumin A.N. Diastolic dysfunction of the right ventricle in coronary heart disease patients. Russian Journal of Cardiology. 2017; 3: 37–45 (in Russ.). DOI: 10.15829/1560-4071-2017-3-37-45
  27. Alam M., Wardell J., Andersson E., Samad B.A., Nordlander R. Right ventricular function in patients with first inferior myocardial infarction: assessment by tricuspid annular motion and tricuspid annular velocity. Am. Heart J. 2000; 139 (4): 710–715. DOI: 10.1016/ s00028703(00)90053-x

About Authors


 If you found mistakes, select text and press Alt+A