Clinical Physiology of Circulation

Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery


Cardioprotective effects of sevoflurane in pediatric congenital heart disease corrective surgery

Authors: O.A. Stepanicheva, M.M. Rybka

Company:
Bakoulev National Medical Research Center for Cardiovascular Surgery, Ministry of Health of the Russian Federation

E-mail: Сведения доступны для зарегистрированных пользователей.

DOI: https://doi.org/10.24022/1814-6910-2019-16-2-85-93

UDC: 616.12-007-053.2-089:615.211

Link: Clinical Physiology of Blood Circulaiton. 2019; 16 (2): 85-93

Quote as: Stepanicheva O.A., Rybka M.M. Cardioprotective effects of sevoflurane in pediatric congenital heart disease corrective surgery. Clinical Physiology of Circulation. 2019; 16 (2): 85–93 (in Russ.). DOI: 10.24022/1814-6910-2019-16- 2-85-93

Received / Accepted:  January 31, 2019 / February 4, 2019

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Abstract

Cardioprotective effect of volatile anesthetics in cardiac surgery with the use of cardiopulmonary bypass (CPB), has been studied starting from the 20th century and has been fully confirmed in adult patients and applied in clinical practice. Yet, in pediatric cardiac surgery the cardioprotective effect of halogene-containing anesthetics is still being looked into. This article contains the current understanding of the mechanisms of preconditioning and organoprotection, a review of the most significant research papers on cardioprotection effect in adult patients. The author has also described and analyzed the existing studies of anesthetic preconditioning in pediatric congenital heart disease corrective surgery with CPB.

About Authors

  • O'lga A. Stepanicheva, Anesthesiologist-Intensivist; ORCID

  • Mikhail M. Rybka, Dr. Med. Sc., Head of Department of Anesthesiology and Intensive Care; ORCID


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