Clinical Physiology of Circulation

ISSN 1814-6910 (Print)
ISSN 2410-9134 (Online)

 

Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery


Issue's catalogue ➤ КФК. 2018; 15 (4): 237-299 ➤ Изменения деформации миокарда левого желудочка у больных ишемической болезнью сердца при стресс-эхокардиографии

Changes in myocardial deformation of the left ventricle in patientswith ischemic heart disease under stress echocardiography

Authors: S.D. Pirtskhalava, E.U. Asymbekova, N.K. Akhmedyarova, A.Z. Rakhimov, V.Yu. Buziashvili, E.F. Tugeeva, S.T. Matskeplishvili, Yu.I. Buziashvili

Company:
Bakoulev National Medical Research Center for Cardiovascular Surgery, Ministry of Health of the Russian Federation, Rublevskoe shosse, 135, Moscow, 121552, Russian Federation

E-mail: Сведения доступны для зарегистрированных пользователей.

DOI: https://doi.org/10.24022/1814-6910-2018-15-4-249-260

UDC: 616.124.2-007.24:616.12-005.4]-073.43

Link: Clinical Physiology of Blood Circulaiton. 2018; 15 (4): 249-260

Quote as: Pirtskhalava S.D., Asymbekova E.U., Akhmedyarova N.K., Rakhimov A.Z., Buziashvili V.Yu., Tugeeva E.F., Matskeplishvili S.T., Buziashvili Yu.I. Changes in myocardial deformation of the left ventricle in patients with ischemic heart disease under stress echocardiography. Clinical Physiology of Circulation. 2018; 15 (4): 249–60 (in Russ.). DOI: 10.24022/1814-6910-2018-15-4-249-260

Keywords:  stress echocardiography echocardiography myocardial ischemia myocardial deformation left ventricle ischemic heart disease

Received / Accepted:  05.07.2018/12.08.2018

Full text:  

Abstract

Objective. To determine the value of deformation of the myocardium (DM) as a diagnostic marker of myocardial ischemia in stress-echocardiography in patients with ischemic heart disease (IHD).

Material and methods. 51 people were examined, including 17 control groups, 34 – patients with IHD. All examined included stress echocardiography with the study of myocardial deformation by tissue dopplerography. The reference method is coronaroangiography.

Results. According to the results of the survey, it was found that in healthy individuals the loading test is accompanied by an increase in deformation and strain rate. In patients with IHD at rest, DM is significantly lower than in the control group (p=0.0001), with stress echocardiography there is a decrease in DM and strain rate. The degree of change in the ejection fraction (EF) and the degree of change in the DM at a load relative to the initial level differ significantly. Changes in DM significantly exceeded the degree of decrease in EF (DM 24.5±14.3%, EF 9.07±13.9%; p =0.00004, 95% CI 8.7 – 22.09).

Conclusion. The study of myocardial deformation in stress echocardiography in addition to the traditional indices of systolic and diastolic function plays an important role in the diagnosis of IHD.

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About Authors

  • Pirtskhalava Sofia Davidovna, Postgraduate; orcid.org/0000-0001-6305-5365
  • Asymbekova El'mira Umetovna, Dr. Med. Sc., Leading Researcher; orcid.org/0000-0002-5422-2069
  • Akhmedyarova Nazli Kerimovna, Cand. Med. Sc., Researcher; orcid.org/0000-0001-7157-6312
  • Rakhimov Akmal Zakriyaevich, Cand. Med. Sc., Researcher; orcid.org/0000-0002-9370-9419
  • Buziashvili Viktoriya Yur'evna, Cand. Med. Sc., Cardiologist
  • Tugeeva El'vina Faatovna, Dr. Med. Sc., Senior Researcher
  • Matskeplishvili Simon Teymurazovich, Dr. Med. Sc., Professor, Corresponding Member of the Russian Academy of Sciences
  • Buziashvili Yuriy Iosifovich, Dr. Med. Sc., Professor, Academician of the Russian Academy of Sciences, Head of Clinical and Diagnostic Department

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