Clinical Physiology of Circulation

Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery


Mitral regurgitation depending on the degree of lesions to the coronary arteries in acute coronary syndrome

Authors: Bockeria L.A., Dzeytova A.Kh.

Company:
Bakoulev National Medical Research Center for Cardiovascular Surgery, Moscow, 121552, Russian Federation

E-mail: Сведения доступны для зарегистрированных пользователей.

DOI: https://doi.org/10.24022/1814-6910-2021-18-1-53-5

UDC: 616.132.2

Link: Clinical Physiology of Blood Circulaiton. 2021; 1 (18): 53-59

Quote as: Bockeria L.A., Dzeytova A.Kh. Mitral regurgitation depending on the degree of lesions to the coronary arteries in acute coronary syndrome. Clinical Physiology of Circulation. 2021; 18 (1): 53–9 (in Russ.). DOI: 10.24022/1814-6910-2021-18-1-53-59

Received / Accepted:  29.01.2021 / 07.02.2021

Full text:  

Abstract

Objective: To analyze the features of mitral regurgitation in patients with acute coronary syndrome depending on the degree of coronary artery lesions.

Material and methods. The research involved 61 patients which were brought to the emergency department of the Republican hospital of Ingushetia with a diagnosis of acute coronary syndrome. The average age of patients is 58 years. The study conducted a comparative analysis of mitral regurgitation in single-vessel and multi-vessel coronary artery lesions. Data on the quantitative assessment of mitral regurgitation in multi-vascular lesions with calculations on the SYNTAX Score scale are presented. The study was conducted on the GE Logic P5 device. The main indicator for the comparative assessment of mitral valve insufficiency was the regurgitation fraction, which was calculated using the PISA (proximal isovelocity surface area) method – the study of the proximal regurgitation zone. To quantify the degree of coronary artery damage, the SYNTAX Score scale was used. Data was analyzed using the statistical computing environment R 3.6.3 (R Foundation for Statistical Computing, Vienna, Austria).

Results. In patients with a single-vessel lesion, the anterior coronary artery is more often involved, which is most likely due to a violation of the blood supply to the papillary muscles or myocardial asynchrony. In patients with damage to the anterior interventricular branch, mitral regurgitation develops less frequently, which is associated with compensatory blood supply capabilities. When comparing patients with single-vessel and multi-vessel lesions, the following results were found: in patients with multi-vessel lesions, the degree of regurgitation is greater than in single-vessel lesions. A direct correlation is observed when comparing the results of echocardiography fad the results of evaluation of coronary artery damage on the SYNTAX Score scale.

Conclusion. Direct correlation between the degree of mitral regurgitation in acute coronary syndrome in patients with multi-vessel disease and SYNTAX Score scale may have a prognostic role in optimizing patient management.

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About Authors

  • Leo A. Bockeria, Dr. Med. Sc., Professor, Academician of RAS and RAMS, President; ORCID
  • Aminat Kh. Dzeytova, Postgraduate; ORCID

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