Clinical Physiology of Circulation

Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery


Microcirculation in a critical patient

Authors: Kuligin A.V., Zeulina E.E.

Company:
Razumovsky Saratov State Medical University, Saratov, Russian Federation

E-mail: Сведения доступны для зарегистрированных пользователей.

DOI: https://doi.org/10.24022/1814-6910-2022-19-1-82-89

UDC: 612.15:615.099.036.11

Link: Clinical Physiology of Blood Circulaiton. 2022; 1 (19): 82-89

Quote as: Kuligin A.V., Zeulina E.E. Microcirculation in a critical patient. Clinical Physiology of Circulation. 2022; 19 (1): 82–9 (in Russ.). DOI: 10.24022/1814-6910-2022-19-1-82-89

Received / Accepted:  19.11.2021 / 30.11.2021

Full text:  

Abstract

The cardiovascular system is mastered by students when they receive higher education according to specialty programs based on an anatomical and physiological approach, and the circulatory system at the stage of training highly qualified personnel should be considered from the position of a functional systemic approach. In the functional circulatory system, subsystems are required, which are united by elements that are different in ontogeny. Microcirculation, along with gas exchange, are subsystems of the functional circulatory system. When determining the basis of microcirculation disorders in a critically ill patient, it is necessary to take into account the role of microcirculation in the development of macrocirculation disorders leading to organ dysfunction and failure. Central hemodynamic research methods do not reveal microcirculatory dysfunction and its response to intensive therapy, which can aggravate the violation of perfusion-metabolic relations and lead to dysfunction and organ failure. From this point of view, the cause of microcirculation dysfunction must be sought in the violation of perfusion-metabolic relationships, as a mechanism for the development of a critical state of the patient, the pathognomonic sign of which is a system of multiple acute dysfunctions.

References

  1. Садчиков Д.В., Кулигин А.В., Зеулина Е.Е., Фисун А.М., Садчиков Д.Д. Функциональный системный подход в преподавании специальности «анестезиология и реаниматология»: учебное пособие. Саратов: Саратовский ГМУ; 2019: 210–48.
  2. Колмогоров А.Н. Элементы теории функций и функционального анализа. М.: Наука; 1976.
  3. Мышкин К.И. Методы программного моделирования обучения факультетской хирургии. Саратов; 1972.
  4. Рыжков И.А., Заржецкий Ю.В., Новодержкина И.С. Сравнительные аспекты регуляции кожной и мозговой микроциркуляции при острой кровопотере. Общая реаниматология. 2017; 13 (6): 18–27. DOI: 10.15360/1813-9779-2017-6-18-27
  5. Мороз В.В., Рыжков И.А. Острая кровопотеря: регионарный кровоток и микроциркуляция (Обзор, часть I). Общая реаниматология. 2016; 12 (2): 66–89. DOI: 10.15360/1813-9779-2016-2-66-89
  6. Мороз В.В., Рыжков И.А. Острая кровопотеря: регионарный кровоток и микроциркуляция (Обзор, часть II). Общая реаниматология. 2016; 12 (5): 65–94. DOI: 10.15360/1813-9779-2016-5-65-94
  7. Садчиков Д.В., Котов С.Н., Родионова Т.В. Температурная реакция при острых нарушениях мозгового кровообращения. Общая реаниматология. 2014; 10 (2): 66–75.
  8. Садчиков Д.В., Кулигин А.В. Cиндром множественной органной дисфункции у больных в остром периоде комы. Саратовский научно-медицинский журнал. 2011; 7 (1): 69–72.
****
  1. Sadchikov D.V., Kuligin A.V., Zeulina E.E., Fisun A.M., Sadchikov D.D. Functional systemic approach to teaching the course in Anesthesiology and Intensive Care Medicine: The tutorial. Saratov; 2019: 210–48 (in Russ.).
  2. Kolmogorov A.N. Elements of the theory of functions and functional analysis. Moscow: Nauka; 1976 (in Russ.).
  3. Myshkin K.I. Methods for software modeling education faculty surgery. Saratov; 1972 (in Russ.).
  4. Ryzhkov I.A., Zarzhetsky Yu.V., Novoderzhkina I.S. Comparative aspects of the regulation of cutaneous and cerebral microcirculation during acute blood loss. General Reanimatology. 2017; 13 (6): 18–27 (in Russ.). DOI: 10.15360/1813-9779-2017-6-18-27
  5. Moroz V.V., Ryzhkov I.A. Acute blood loss: regional blood flow and microcirculation (Review, Part I). General Reanimatology. 2016; 12 (2): 66–89 (in Russ.). DOI: 10.15360/1813-9779-2016-2-66-89
  6. Moroz V.V., Ryzhkov I.A. Acute blood loss: regional blood flow and microcirculation (Review, Part II). General Reanimatology. 2016; 12 (5): 65–94 (in Russ.). DOI: 10.15360/1813-9779-2016-5-65-94
  7. Sadchikov D.V., Kotov S.N., Rodionova T.V. Temperature response in acute cerebrovascular accidents. General Reanimatology. 2014; 10 (2): 66–75 (in Russ.).
  8. Sadchikov D.V., Kuligin A.V. Multiorgan dysfunction syndrome in patients in acute period of coma. Saratov Journal of Medical Scientific Research. 2011; 7 (1): 69–72 (in Russ.).

About Authors

  • Aleksandr V. Kuligin, Dr. Med. Sci., Associate Professor, Chief of Chair of Emergency, Anesthesiology Reanimatology Care and Simulation Technologies in Medicine; ORCID
  • Ekaterina E. Zeulina, Cand. Med. Sci., Associate Professor of Chair of Emergency, Anesthesiology Reanimatology Care and Simulation Technologies in Medicine; ORCID

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